Gene transfer in humans using a conditionally replicating lentiviral vector (Q24675343)

10

object named as

John R Mascola

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Carl H. June

13

object named as

Carl H June

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Bruce L. Levine

1

object named as

Bruce L Levine

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author name string

Laurent M Humeau

2

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Jean Boyer

3

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Rob-Roy MacGregor

4

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Tessio Rebello

5

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Xiaobin Lu

6

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Gwendolyn K Binder

7

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Vladimir Slepushkin

8

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Franck Lemiale

9

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Boro Dropulic

Proceedings of the National Academy of Sciences of the United States of America

12

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language of work or name

English

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publication date

14 November 2006

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published in

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volume

103

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issue

46

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page(s)

17372-7

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cites work

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Silencing and variegation of gammaretrovirus and lentivirus vectors

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Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector

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Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection

28 September 2017

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A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread

28 September 2017

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28 September 2017

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Clinical protocol. A phase 1 open-label clinical trial of the safety and tolerability of single escalating doses of autologous CD4 T cells transduced with VRX496 in HIV-positive subjects.

30 May 2018

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Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation

30 May 2018

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Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Ev

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Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol.

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Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.

21 January 2018

1 reference

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Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load

21 January 2018

1 reference

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A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy

21 January 2018

1 reference

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Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips".

21 January 2018

1 reference

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Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1.

21 January 2018

1 reference

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A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17090675

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0608138103

1 reference

407019

ADS bibcode

2006PNAS..10317372L

0 references

407019

1 reference

1 reference

1 reference