Molecular actions of vitamin D contributing to cancer prevention (Q24654260)

Molecular Aspects of Medicine

Europe PubMed Central

title

Molecular actions of vitamin D contributing to cancer prevention (English)

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James C Fleet

1

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language of work or name

English

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publication date

December 2008

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published in

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volume

29

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issue

6

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page(s)

388-96

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cites work

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The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.

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1alpha,25-Dihydroxyvitamin D(3) antiproliferative actions involve vitamin D receptor-mediated activation of MAPK pathways and AP-1/p21(waf1) upregulation in human osteosarcoma

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Commentary: vitamin D and colorectal cancer--twenty-five years later

28 September 2017

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Molecular mechanisms mediating the anti-proliferative effects of Vitamin D in prostate cancer

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Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes

28 September 2017

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28 September 2017

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Mounting evidence for vitamin D as an environmental factor affecting autoimmune disease prevalence.

28 September 2017

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Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays

28 September 2017

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Vitamin D receptor and p21/WAF1 are targets of genistein and 1,25-dihydroxyvitamin D3 in human prostate cancer cells

28 September 2017

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Molecular analysis of p21 promoter activity isolated from squamous carcinoma cell lines of the head and neck under the influence of 1,25(OH)2 vitamin D3 and its analogs

28 September 2017

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Identification of a functional vitamin D response element in the human insulin-like growth factor binding protein-3 promoter

28 September 2017

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The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes

28 September 2017

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Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer

28 September 2017

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Growth inhibitory effects of 1alpha, 25-dihydroxyvitamin D(3) are mediated by increased levels of p21 in the prostatic carcinoma cell line ALVA-31.

28 September 2017

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Regulation of proliferation of prostate epithelial cells by 1,25-dihydroxyvitamin D3 is accompanied by an increase in insulin-like growth factor binding protein-3.

28 September 2017

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1,25(OH)2 vitamin D3 induces elevated expression of the cell cycle-regulating genes P21 and P27 in squamous carcinoma cell lines of the head and neck

28 September 2017

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28 September 2017

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1alpha-Hydroxylase and the action of vitamin D.

28 September 2017

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The multifunctional properties and characteristics of vitamin D-binding protein

28 September 2017

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Apoptosis is induced by the active metabolite of vitamin D3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: possible implications for prevention and therapy

28 September 2017

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28 September 2017

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Mitogen-activated protein kinase inhibits 1,25-dihydroxyvitamin D3-dependent signal transduction by phosphorylating human retinoid X receptor alpha

28 September 2017

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Increasing the complexity of coactivation in nuclear receptor signaling

28 September 2017

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Antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation

28 September 2017

1 reference

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Vitamin D receptor content and transcriptional activity do not fully predict antiproliferative effects of vitamin D in human prostate cancer cell lines

28 September 2017

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Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

28 September 2017

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Do sunlight and vitamin D reduce the likelihood of colon cancer?

28 September 2017

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Late endosomes derive from early endosomes by maturation

28 September 2017

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Vitamin D receptor expression is required for growth modulation by 1 alpha,25-dihydroxyvitamin D3 in the human prostatic carcinoma cell line ALVA-31.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

Stable expression of the nuclear vitamin D receptor in the human prostatic carcinoma cell line JCA-1: evidence that the antiproliferative effects of 1 alpha, 25-dihydroxyvitamin D3 are mediated exclusively through the genomic signaling pathway

28 September 2017

1 reference

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1,25-Dihydroxyvitamin D3 translocates protein kinase C beta to nucleus and enhances plasma membrane association of protein kinase C alpha in renal epithelial cells

28 September 2017

1 reference

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Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation

28 September 2017

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Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.

30 May 2018

1 reference

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Dimerization with retinoid X receptors promotes nuclear localization and subnuclear targeting of vitamin D receptors

30 May 2018

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Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

30 May 2018

1 reference

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The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.

30 May 2018

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Differential effects of 1,25-dihydroxyvitamin D3 and tetradecanoylphorbol acetate on cell cycle and apoptosis of MCF-7 cells and a vitamin D3-resistant variant

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

Vitamin D analogues up-regulate p21 and p27 during growth inhibition of pancreatic cancer cell lines

30 May 2018

1 reference

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Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines

30 May 2018

1 reference

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Role of 25-hydroxyvitamin D3 dose in determining rat 1,25-dihydroxyvitamin D3 production

30 May 2018

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Immunocytology with microwave-fixed fibroblasts shows 1 alpha,25-dihydroxyvitamin D3-dependent rapid and estrogen-dependent slow reorganization of vitamin D receptors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

CYP27A1 and CYP24 expression as a function of malignant transformation in the colon.

30 May 2018

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Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis.

28 November 2018

1 reference

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Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

25-hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

Retinoid X receptor dominates the nuclear import and export of the unliganded vitamin D receptor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

Regulation of gene Expression by 1alpha,25-dihydroxyvitamin D3 and Its analog EB1089 under growth-inhibitory conditions in squamous carcinoma Cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

Reduced 1alpha-hydroxylase activity in human prostate cancer cells correlates with decreased susceptibility to 25-hydroxyvitamin D3-induced growth inhibition

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613446

Regulation of insulin-like growth factor (IGF) II and IGF binding protein 3 autocrine loop in human PC-3 prostate cancer cells by vitamin D metabolite 1,25(OH)2D3 and its analog EB1089.

28 November 2018

1 reference

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1,25-dihydroxyvitamin D3 and malignant melanoma: the presence of receptors and inhibition of cell growth in culture

28 November 2018

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12 December 2020

The role of vitamin D3 in the proliferation of a human colon cancer cell line in vitro

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12 December 2020

Effect of 1,25-dihydroxyvitamin D3 on mouse mammary tumor (GR) cells: evidence for receptors, cellular uptake, inhibition of growth and alteration in morphology at physiologic concentrations of hormone

1 reference

12 December 2020

Growth inhibition of both MCF-7 and Hs578T human breast cancer cell lines by vitamin D analogues is associated with increased expression of insulin-like growth factor binding protein-3

1 reference

12 December 2020

Vitamin D analogue EB1089-induced prostate regression is associated with increased gene expression of insulin-like growth factor binding proteins

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12 December 2020

Subcellular distribution of normal and mutant vitamin D receptors in living cells. Studies with a novel fluorescent ligand

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12 December 2020

Tumor suppressor genes

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Crossref

https://api.crossref.org/works/10.1016%2FJ.MAM.2008.07.003

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.MAM.2008.07.003

1 reference

682519

682519

1 reference

1 reference

1 reference