The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44 (Q24617130)

2

0 references

Bigang Liu

3

0 references

Xin Chen

4

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Tammy Calhoun-Davis

5

0 references

Hangwen Li

6

0 references

Lubna Patrawala

7

0 references

Hong Yan

8

0 references

Collene Jeter

9

0 references

Sofia Honorio

10

0 references

Jason F Wiggins

11

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Andreas G Bader

12

0 references

Randy Fagin

13

0 references

David Brown

14

0 references

Dean G Tang

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells

15

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language of work or name

English

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publication date

February 2011

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published in

Nature Medicine

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volume

17

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page(s)

211-5

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issue

2

0 references

cites work

1 reference

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miR-34a repression of SIRT1 regulates apoptosis

7 April 2017

1 reference

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Identification and characterization of ovarian cancer-initiating cells from primary human tumors

7 April 2017

1 reference

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Phenotypic characterization of human colorectal cancer stem cells

7 April 2017

1 reference

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Prospective identification of tumorigenic breast cancer cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Oncomirs - microRNAs with a role in cancer

7 April 2017

1 reference

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Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34

7 April 2017

1 reference

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The miR-34 family in cancer and apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

7 April 2017

1 reference

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Significance of CD90+ cancer stem cells in human liver cancer

7 April 2017

1 reference

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let-7 regulates self renewal and tumorigenicity of breast cancer cells

7 April 2017

1 reference

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The let-7 microRNA represses cell proliferation pathways in human cells

7 April 2017

1 reference

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A microRNA component of the p53 tumour suppressor network

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Identification of pancreatic cancer stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Prospective identification of tumorigenic prostate cancer stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

miRNAs, cancer, and stem cell division

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

7 April 2017

1 reference

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MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Methodologies in assaying prostate cancer stem cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Identification of gastric cancer stem cells using the cell surface marker CD44.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Functional evidence that the self-renewal gene NANOG regulates human tumor development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076220

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2284

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2284

Deletion of the WNT Target and Cancer Stem Cell Marker CD44 in Apc(Min/+) Mice Attenuates Intestinal Tumorigenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2284

21 January 2018

Identifiers

DOI

10.1038/NM.2284

1 reference

Dimensions Publication ID

446148

1051843869

0 references

446148

1 reference

1 reference

1 reference