Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase (Q24562843)

1

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T B Ahmad

2

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G W Carlile

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D Pappin

4

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R P Narsimhan

5

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S C Ley

cPLA2 is phosphorylated and activated by MAP kinase

6

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language of work or name

English

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publication date

15 February 1996

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published in

The EMBO Journal

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volume

15

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issue

4

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page(s)

817-26

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cites work

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Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1

24 March 2017

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

24 March 2017

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

24 March 2017

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ATF-2 contains a phosphorylation-dependent transcriptional activation domain

24 March 2017

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Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

24 March 2017

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Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

24 March 2017

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Structure and transforming potential of the human cot oncogene encoding a putative protein kinase

24 March 2017

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Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein

24 March 2017

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Expression cDNA cloning of a serine kinase transforming gene

24 March 2017

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Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

24 March 2017

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A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

24 March 2017

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Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

24 March 2017

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

24 March 2017

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MAP kinase pathways in yeast: for mating and more

24 March 2017

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

24 March 2017

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

24 March 2017

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Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

24 March 2017

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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

24 March 2017

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STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast

24 March 2017

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Dominant mutations in a gene encoding a putative protein kinase (BCK1) bypass the requirement for a Saccharomyces cerevisiae protein kinase C homolog

24 March 2017

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Activation of the MAP kinase pathway by the protein kinase raf

24 March 2017

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Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

24 March 2017

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Raf-1 activates MAP kinase-kinase

24 March 2017

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

24 March 2017

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

7 April 2017

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The stress-activated protein kinase subfamily of c-Jun kinases

7 April 2017

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Transformation of mammalian cells by constitutively active MAP kinase kinase

7 April 2017

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Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

7 April 2017

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

7 April 2017

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

7 April 2017

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

7 April 2017

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Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion.

7 April 2017

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A conserved kinase cascade for MAP kinase activation in yeast.

27 September 2017

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Raf-1 is required for T cell IL2 production.

27 September 2017

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MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

27 September 2017

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Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.

27 September 2017

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Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

27 September 2017

1 reference

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Transcriptional regulation by extracellular signals: mechanisms and specificity

27 September 2017

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The Ras signaling pathway in Drosophila

27 September 2017

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Ras pathways in Caenorhabditis elegans

27 September 2017

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Parallel signal processing among mammalian MAPKs

27 September 2017

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Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

27 September 2017

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T cell growth factor receptors. Quantitation, specificity, and biological relevance

27 September 2017

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byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype

27 September 2017

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Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6.

27 September 2017

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JNK is involved in signal integration during costimulation of T lymphocytes.

27 September 2017

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Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation

27 September 2017

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Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro

27 September 2017

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A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras.

30 May 2018

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The murine cot proto-oncogene: genome structure and tissue-specific expression.

30 May 2018

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The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo

30 May 2018

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30 May 2018

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Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

30 May 2018

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MAP kinase activation is essential for oncogenic transformation of NIH3T3 cells by Mos.

30 May 2018

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MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase

30 May 2018

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A one-step purification of membrane proteins using a high efficiency immunomatrix

30 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8631303

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8631303

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

4593617

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference