Mammalian dihydroorotase: nucleotide sequence, peptide sequences, and evolution of the dihydroorotase domain of the multifunctional protein CAD (Q24559935)

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Language	Label	Description	Also known as
English	Mammalian dihydroorotase: nucleotide sequence, peptide sequences, and evolution of the dihydroorotase domain of the multifunctional protein CAD	scientific article

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scholarly article

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Mammalian dihydroorotase: nucleotide sequence, peptide sequences, and evolution of the dihydroorotase domain of the multifunctional protein CAD (English)

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protein evolution

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author name string

J P Simmer

1

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R E Kelly

2

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A G Rinker

3

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B H Zimmermann

4

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J L Scully

5

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H Kim

6

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D R Evans

7

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language of work or name

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publication date

January 1990

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Proceedings of the National Academy of Sciences of the United States of America

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87

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1

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174-8

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Phosphorylation and activation of hamster carbamyl phosphate synthetase II by cAMP-dependent protein kinase. A novel mechanism for regulation of pyrimidine nucleotide biosynthesis

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24 March 2017

DNA sequencing with chain-terminating inhibitors

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24 March 2017

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

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24 March 2017

Structure of the Saccharomyces cerevisiae URA4 gene encoding dihydroorotase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

24 March 2017

Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. I. Dihydroortic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

24 March 2017

Pyrimidine metabolism in man. I. The biosynthesis of orotic acid

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

Controlled proteolysis of the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells: evidence for discrete structural domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

Mammalian aspartate transcarbamylase (ATCase): sequence of the ATCase domain and interdomain linker in the CAD multifunctional polypeptide and properties of the isolated domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

Interconversion of carbamayl-L-aspartate and L-dihydroorotate by dihydroorotase from mouse Ehrlich ascites carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

Purification from hamster cells of the multifunctional protein that initiates de novo synthesis of pyrimidine nucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

Isolation of a multifunctional complex containing the first three enzymes of pyrimidine biosynthesis inDrosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

Purification of properties of dihydroorotase, a zinc-containing metalloenzyme in Clostridium oroticum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

An evolutionary tree for invertebrate globin sequences

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

27 September 2017

The isolation and characterization of the aspartate transcarbamylase domain of the multifunctional protein, CAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

Catalytic synergy in the multifunctional protein that initiates pyrimidine biosynthesis in Syrian hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

The effects of pH and inhibitors upon the catalytic activity of the dihydroorotase of multienzymatic protein pyr1-3 from mouse Ehrlich ascites carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

Functional diversity within the rudimentary locus of Drosophila melanogaster.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

cis-4-Carboxy-6-(mercaptomethyl)-3,4,5,6-tetrahydropyrimidin-2(1 H)-one , a potent inhibitor of mammalian dihydroorotase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

The rudimentary gene of Drosophila melanogaster encodes four enzymic functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

Nucleotide sequence of the structural gene for dihydroorotase of Escherichia coli K12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

Cloning and structural characterization of the Salmonella typhimurium pyrC gene encoding dihydroorotase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

The dihydroorotase domain of the multifunctional protein CAD. Subunit structure, zinc content, and kinetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

Dihydroorotase from Escherichia coli. Cloning the pyrC gene and production of tryptic peptide maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

Immunochemical analysis of the domain structure of CAD, the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

The primary structure of the aspartate transcarbamylase region of the URA2 gene product in Saccharomyces cerevisiae. Features involved in activity and nuclear localization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

A complex genetic locus that controls of the first three steps of pyrimidine biosynthesis in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

The overall synthesis of L-5,6-dihydroorotate by multienzymatic protein pyr1-3 from hamster cells. Kinetic studies, substrate channeling, and the effects of inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

A unique signature identifies a family of zinc-dependent metallopeptidases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

30 May 2018

Expression, identification, and characterization of recombinant gene products in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53223

19 June 2018

Organization of a multifunctional protein in pyrimidine biosynthesis. Analyses of active, tryptic fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydroorotase from Escherichia coli. Purification and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STUDIES ON DIHYDROOROTASE ACTIVITY IN PREPARATIONS FROM NOVIKOFF ASCITES HEPATOMA CELLS

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for function of a metal ion in the activity of dihydroorotase from Zymobacterium oroticum

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and properties of dihydroorotase from Escherichia coli B

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial steps in pyrimidine synthesis in ehrlich ascites carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydroorotase from rat liver: purification, properties and regulatory role in pyrimidine biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of a Dictyostelium discoideum gene encoding a multifunctional enzyme of the pyrimidine pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/1967494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.87.1.174

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1990PNAS...87..174S

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