Glucokinase regulatory protein gene polymorphism affects postprandial lipemic response in a dietary intervention study (Q24338412)

GOA release 2020-03-11

triglyceride homeostasis

1 reference

GOA release 2020-03-11

1 reference

Braxton D Mitchell

5

0 references

Alan R. Shuldiner

Alan R Shuldiner

6

0 references

Toni I Pollin

2

Toni I Pollin

0 references

Coleen M Damcott

3

Coleen M Damcott

0 references

Haiqing Shen

1

Haiqing Shen

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John C McLenithan

4

https://scigraph.springernature.com/pub.10.1007/s00439-009-0700-3

John C McLenithan

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language of work or name

English

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publication date

October 2009

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published in

Human Genetics

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volume

126

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issue

4

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page(s)

567-74

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exact match

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cites work

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

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Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation

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Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states

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The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population

27 September 2017

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The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study

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Postprandial fatty acid metabolism in the development of lipotoxicity and type 2 diabetes

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The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

27 September 2017

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Novel polymorphisms in the GCKR gene and their influence on glucose and insulin levels in a Danish twin population

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27 September 2017

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27 September 2017

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Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins (TRL) to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters.

30 May 2018

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30 May 2018

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Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians

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29 November 2018

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Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance.

29 November 2018

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Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia.

29 November 2018

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