Phosphodiesterase 4D regulates baseline sarcoplasmic reticulum Ca2+ release and cardiac contractility, independently of L-type Ca2+ current (Q24337525)

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

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regulation of cardiac muscle cell contraction

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Phosphodiesterase 4D, cAMP specific

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ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

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author name string

Sanja Beca

1

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Peter B Helli

2

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Jeremy A Simpson

3

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Dongling Zhao

4

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Gerrie P Farman

5

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Peter P Jones

6

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Xixi Tian

7

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Lindsay S Wilson

8

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Faiyaz Ahmad

9

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S R Wayne Chen

10

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Matthew A Movsesian

11

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Vincent Manganiello

12

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Donald H Maurice

13

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Marco Conti

14

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Peter H Backx

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

15

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language of work or name

English

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publication date

14 October 2011

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published in

Circulation Research

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volume

109

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issue

9

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page(s)

1024-30

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Phosphodiesterase III inhibitors for heart failure

19 March 2017

1 reference

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Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Conserved expression and functions of PDE4 in rodent and human heart

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Targeting cyclic nucleotide phosphodiesterase in the heart: therapeutic implications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes

27 September 2017

1 reference

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Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials

27 September 2017

1 reference

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cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Myocardial phosphodiesterases and regulation of cardiac contractility in health and cardiac disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts.

27 September 2017

1 reference

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Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging

27 September 2017

1 reference

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PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

27 September 2017

1 reference

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Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

27 September 2017

1 reference

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Inhibition of glycogenolysis in isolated rat hepatocytes by the Rp diastereomer of adenosine cyclic 3‘,5‘-phosphorothioate

27 September 2017

1 reference

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The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

PI3Kgamma is required for PDE4, not PDE3, activity in subcellular microdomains containing the sarcoplasmic reticular calcium ATPase in cardiomyocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

Cardiac sarcoplasmic reticulum calcium release and load are enhanced by subcellular cAMP elevations in PI3Kgamma-deficient mice

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4138878

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

29 November 2018

1 reference

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Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents

29 November 2018

1 reference

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10.1161/CIRCRESAHA.111.250464

29 November 2018

Identifiers

DOI

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2590933

2590933

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1 reference

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