Thymidylate synthase as an oncogene: a novel role for an essential DNA synthesis enzyme (Q24337187)

GOA release 2020-03-11

DNA biosynthetic process

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GOA release 2020-03-11

author name string

Lambratu Rahman

1

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Donna Voeller

2

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Monzur Rahman

3

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Stan Lipkowitz

4

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Carmen Allegra

5

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J Carl Barrett

6

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Frederic J Kaye

7

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Maria Zajac-Kaye

The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro

8

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language of work or name

English

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publication date

April 2004

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published in

Cancer Cell

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volume

5

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issue

4

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page(s)

341-51

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Mutagenicity of thymidine to cultured Chinese hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

1 reference

7 January 2021

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Thymidylate synthase inhibitors as anticancer agents: from bench to bedside

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by thymidine and suppressed by deoxycytidine

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Transcriptional control elements and complex initiation pattern of the TATA-less bidirectional human thymidylate synthase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Ribonucleotide reductase R2 component is a novel malignancy determinant that cooperates with activated oncogenes to determine transformation and malignant potential

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

The R1 component of mammalian ribonucleotide reductase has malignancy-suppressing activity as demonstrated by gene transfer experiments

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Regulation of cell proliferation by the E2F transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Predictive and prognostic markers in gastrointestinal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Disruption of Myc-tubulin interaction by hyperphosphorylation of c-Myc during mitosis or by constitutive hyperphosphorylation of mutant c-Myc in Burkitt's lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Clinical significance of thymidylate synthase expression in bladder cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Prognostic importance of thymidylate synthase expression in early breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Thymidylate synthase and drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

The myc intron-binding polypeptide associates with RFX1 in vivo and binds to the major histocompatibility complex class II promoter region, to the hepatitis B virus enhancer, and to regulatory regions of several distinct viral genes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

New prognostic indicator for non-small-cell lung cancer, quantitation of thymidylate synthase by real-time reverse transcription polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Enhanced expression of thymidylate synthase may be of prognostic importance in advanced cervical cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Sibling rivalry in the E2F family

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

The identification of thymidylate synthase peptide domains located in the interface region that bind thymidylate synthase mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

Multiple members of the E2F transcription factor family are the products of oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

DNAase I encapsulated in liposomes can induce neoplastic transformation of Syrian hamster embryo cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900080-7

7 January 2021

10.1016/S1535-6108(04)00080-7

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

release_borymegfxjcxzbjbacnl3wl54a

4278461

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/borymegfxjcxzbjbacnl3wl54a

24 November 2022

mapped directly with Wikidata item

4278461

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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