The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling (Q24337017)

epidermal growth factor receptor signaling pathway

GOA release 2020-03-11

1 reference

Growth factor receptor bound protein 2

GOA release 2020-03-11

1 reference

signal transducing adaptor protein

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1322798

13 September 2022

signal transduction

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1322798

13 September 2022

2

R. J. Daly

1 reference

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13 September 2022

author name string

E. J. Lowenstein

1

1 reference

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13 September 2022

A. G. Batzer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1322798

13 September 2022

W. Li

4

1 reference

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13 September 2022

B. Margolis

5

1 reference

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13 September 2022

R. Lammers

6

1 reference

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13 September 2022

A. Ullrich

7

1 reference

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13 September 2022

E. Y. Skolnik

8

1 reference

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13 September 2022

D. Bar-Sagi

9

1 reference

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13 September 2022

J. Schlessinger

10

1 reference

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Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase

13 September 2022

language of work or name

English

0 references

publication date

7 August 1992

0 references

published in

Cell

0 references

volume

70

0 references

issue

3

0 references

page(s)

431-42

0 references

cites work

1 reference

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Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells

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Arg-Gly-Asp: a versatile cell recognition signal

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Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

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7 January 2021

EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling

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Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

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cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

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7 January 2021

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

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PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

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Oncogenes and signal transduction

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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Signal transduction by allosteric receptor oligomerization

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SH2 domains: elements that control protein interactions during signal transduction

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A novel viral oncogene with structural similarity to phospholipase C

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Cloning of bovine GAP and its interaction with oncogenic ras p21.

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The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

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7 January 2021

Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva.

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7 January 2021

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

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7 January 2021

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

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Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis

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The scanning model for translation: an update

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High-affinity epidermal growth factor binding is specifically reduced by a monoclonal antibody, and appears necessary for early responses

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Recognition of protein coding regions in DNA sequences

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Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

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Site specificity of casein kinase-2 (TS) from rat liver cytosol. A study with model peptide substrates

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Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements

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Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

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Molecular cloning of two types of GAP complementary DNA from human placenta

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Tyrosine kinase activity is essential for the association of phospholipase C-gamma with the epidermal growth factor receptor

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Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase

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A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

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A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

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Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

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7 January 2021

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

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SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

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7 January 2021

Purification and characterization of human H-ras proteins expressed in Escherichia coli

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7 January 2021

A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps

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7 January 2021

High-efficiency transformation of mammalian cells by plasmid DNA

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7 January 2021

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

3951604

3951604

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference