Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2 (Q24323599)

12 December 2020

Ansig for Windows: an interactive computer program for semiautomatic assignment of protein NMR spectra.

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12 December 2020

The penultimate rotamer library

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12 December 2020

Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

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12 December 2020

High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains

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12 December 2020

Cloning and characterization of GRB14, a novel member of the GRB7 gene family

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12 December 2020

Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor

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12 December 2020

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

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12 December 2020

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

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12 December 2020

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

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12 December 2020

The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10

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12 December 2020

Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide

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12 December 2020

Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands

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12 December 2020

Heteronuclear filters in two-dimensional [1H,1H]-NMR spectroscopy: combined use with isotope labelling for studies of macromolecular conformation and intermolecular interactions

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12 December 2020

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

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12 December 2020

Sequence analysis identifies a ras-associating (RA)-like domain in the N-termini of band 4.1/JEF domains and in the Grb7/10/14 adapter family

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12 December 2020

Thermodynamic and structural analysis of phosphotyrosine polypeptide binding to Grb2-SH2

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12 December 2020

Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide

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12 December 2020

Chemical shift assignments and secondary structure of the Grb2 SH2 domain by heteronuclear NMR spectroscopy

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12 December 2020

The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer

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12 December 2020

Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: applicati

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12 December 2020

Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain

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12 December 2020

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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12 December 2020

The GRB family of SH2 domain proteins

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12 December 2020

Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase

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12 December 2020

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

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12 December 2020

Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7

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12 December 2020

Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner

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12 December 2020

Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

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12 December 2020

Studies on the solution conformation of human thioredoxin using heteronuclear nitrogen-15-proton nuclear magnetic resonance spectroscopy

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12 December 2020

The impact of direct refinement against 13C alpha and 13C beta chemical shifts on protein structure determination by NMR.

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12 December 2020

Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis

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12 December 2020

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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12 December 2020

Pseudoreversion of the catalytic activity of Y14F by the additional substitution(s) of tyrosine with phenylalanine in the hydrogen bond network of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B

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12 December 2020

Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3

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12 December 2020

Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase

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12 December 2020

Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

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12 December 2020

Assignment of backbone 1H, 13C, and 15N resonances of human Grb7-SH2 domain in complex with a phosphorylated peptide ligand

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12 December 2020

mGrb10 interacts with Nedd4

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12 December 2020

Pulsed field gradient multi-dimensional NMR methods for the study of protein structure and dynamics in solution

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12 December 2020

Four-dimensional carbon-13/carbon-13-edited nuclear Overhauser enhancement spectroscopy of a protein in solution: application to interleukin 1.beta

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12 December 2020