Microspherule protein 2 associates with ASK1 and acts as a negative regulator of stress-induced ASK1 activation (Q24323373)

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Fang Zhang

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Liang Da

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Tsaiping Li

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Mujun Zhao

Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length

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language of work or name

English

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publication date

12 June 2012

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published in

FEBS Letters

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volume

586

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page(s)

1678-86

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issue

12

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cites work

1 reference

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Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration

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The nonspecific lethal complex is a transcriptional regulator in Drosophila.

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TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1).

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Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor

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Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

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Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

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The roles of ASK family proteins in stress responses and diseases

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Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

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Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm

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RNAi-mediated inhibition of MSP58 decreases tumour growth, migration and invasion in a human glioma cell line

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The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons

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Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

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Mutant p53 disrupts the stress MAPK activation circuit induced by ASK1-dependent stabilization of Daxx

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Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

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Apoptosis Signal-Regulating Kinase 1 Regulates Colitis and Colitis-Associated Tumorigenesis by the Innate Immune Responses

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Downregulation of MSP58 inhibits growth of human colorectal cancer cells via regulation of the cyclin D1-cyclin-dependent kinase 4-p21 pathway

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