Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin (Q24323262)

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6 January 2020

title

Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin (English)

1 reference

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Proprotein convertase subtilisin/kexin type 7

6 January 2020

main subject

brain

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Furin, paired basic amino acid cleaving enzyme

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Brain protein I3

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Proprotein convertase subtilisin/kexin type 5

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protein processing

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Furin (paired basic amino acid cleaving enzyme)

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Proprotein convertase subtilisin/kexin type 5

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Beta-site APP cleaving enzyme 1

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Proprotein convertase subtilisin/kexin type 7

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Brain protein I3

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4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15606899%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Nabil Seidah

5

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6 January 2020

author name string

Louise Wickham

1

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6 January 2020

Suzanne Benjannet

2

1 reference

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6 January 2020

Edwige Marcinkiewicz

3

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6 January 2020

language of work or name

English

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publication date

1 January 2005

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Journal of Neurochemistry

6 January 2020

published in

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6 January 2020

volume

92

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6 January 2020

issue

1

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6 January 2020

page(s)

93-102

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Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia

6 January 2020

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

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A stop-codon mutation in the BRI gene associated with familial British dementia

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A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

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A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

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Processing of beta-secretase by furin and other members of the proprotein convertase family

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Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines

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Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain

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Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

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Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

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Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

21 January 2018

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Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

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RanBPM, a nuclear protein that interacts with and regulates transcriptional activity of androgen receptor and glucocorticoid receptor

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Subtractive hybridization reveals the expression of immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells

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Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

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The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain

21 January 2018

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The beta-secretase, BACE: a prime drug target for Alzheimer's disease

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Phosphorylation regulates intracellular trafficking of beta-secretase

21 January 2018

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Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM

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21 January 2018

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Coordinated Expression of β-Amyloid Precursor Protein and the Putative β-Secretase BACE and α-Secretase ADAM10 in Mouse and Human Brain

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7 January 2021

Furin is important but not essential for the proteolytic maturation of gp160 of HIV-1

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7 January 2021

bri3, a novel gene, participates in tumor necrosis factor-alpha-induced cell death

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7 January 2021

Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?

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Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family

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BRICHOS: a conserved domain in proteins associated with dementia, respiratory distress and cancer

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7 January 2021

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