Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression (Q24322729)

TATA-box binding protein associated factor 1

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tumor protein p53

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p53 binding

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Post-translational modifications and activation of p53 by genotoxic stresses

3

Hilary M Sheppard

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author name string

Heng-Hong Li

series ordinal

1

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Andrew G Li

series ordinal

2

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Xuan Liu

series ordinal

4

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language of work or name

English

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publication date

26 March 2004

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published in

Molecular Cell

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volume

13

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issue

6

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page(s)

867-78

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cites work

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Stress signals utilize multiple pathways to stabilize p53

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

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Rescuing the function of mutant p53.

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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Casein kinase II is a selective target of HIV-1 transcriptional inhibitors

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TAF-like function of SV40 large T antigen

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TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74

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Cap-independent translation of mRNA conferred by encephalomyocarditis virus 5' sequence improves the performance of the vaccinia virus/bacteriophage T7 hybrid expression system

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Phosphorylation of human p53 on Thr-55.

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pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants

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The CCG1/TAFII250 gene is mutated in thermosensitive G1 mutants of the BHK21 cell line derived from golden hamster

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

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A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

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Ultraviolet-induced junD activation and apoptosis in myeloblastic leukemia ML-1 cells

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The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

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Determination of lymphocyte division by flow cytometry

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Increase in wild-type p53 stability and transactivational activity by the chemopreventive agent apigenin in keratinocytes

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The TAF(II)250 subunit of TFIID has histone acetyltransferase activity

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Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization

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Functional analysis of the human TAFII250 N-terminal kinase domain

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Different functional domains of TAFII250 modulate expression of distinct subsets of mammalian genes

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Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila

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Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation

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The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein

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Apoptosis is induced in BHK cells by the tsBN462/13 mutation in the CCG1/TAFII250 subunit of the TFIID basal transcription factor

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D-type cyclin expression is decreased and p21 and p27 CDK inhibitor expression is increased when tsBN462 CCG1/TAFII250 mutant cells arrest in G1 at the restrictive temperature.

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p53: good cop/bad cop.

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250

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Taf(II) 250 phosphorylates human transcription factor IIA on serine residues important for TBP binding and transcription activity

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Regulation of histone deacetylase 2 by protein kinase CK2.

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Surfing the p53 network

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Promoter-selective transcriptional defect in cell cycle mutant ts13 rescued by hTAFII250.

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TAFII250-dependent transcription of cyclin A is directed by ATF activator proteins

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Defect in the p53-Mdm2 autoregulatory loop resulting from inactivation of TAF(II)250 in cell cycle mutant tsBN462 cells

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7 January 2021

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

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7 January 2021

Nuclear extracellular signal-regulated kinase 2 phosphorylates p53 at Thr55 in response to doxorubicin

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