Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1 (Q24322608)

somatotropin

1 reference

Insulin like growth factor 1

1 reference

Phosphoinositide-3-kinase regulatory subunit 1

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phosphatidylinositol 3-kinase binding

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Janus kinase 2

1 reference

1 reference

1 reference

N Billestrup

4

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author name string

L S Argetsinger

1

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G W Hsu

2

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M G Myers

3

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M F White

5

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C Carter-Su

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

16 June 1995

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published in

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volume

270

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issue

24

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page(s)

14685-92

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cites work

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

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Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

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Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

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Role of IRS-1-GRB-2 complexes in insulin signaling

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Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

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Growth hormone receptor and serum binding protein: purification, cloning and expression

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Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

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Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

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Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants

21 January 2018

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JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

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Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

21 January 2018

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Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation

21 January 2018

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Growth hormone promoted tyrosyl phosphorylation of growth hormone receptors in murine 3T3-F442A fibroblasts and adipocytes

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Improved tools for biological sequence comparison

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Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

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Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

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IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

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Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

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Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone.

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Cloning and in vivo expression of bovine growth hormone receptor mRNA.

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The sheep growth hormone receptor: molecular cloning and ontogeny of mRNA expression in the liver.

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Porcine growth hormone receptor cDNA sequence

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Molecular cloning of the chicken growth hormone receptor complementary deoxyribonucleic acid: mutation of the gene in sex-linked dwarf chickens

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A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells.

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Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

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Oncogenes and signal transduction

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

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Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

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Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites.

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Cellular mechanism of the insulin-like effect of growth hormone in adipocytes. Rapid translocation of the HepG2-type and adipocyte/muscle glucose transporters

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Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

21 January 2018

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Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

21 January 2018

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A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole

21 January 2018

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7 January 2021

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

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7 January 2021

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

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7 January 2021

A general and rapid mutagenesis method using polymerase chain reaction

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7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

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7 January 2021

Molecular cloning of the murine JAK1 protein tyrosine kinase and its expression in the mouse central nervous system.

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7 January 2021