Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway (Q24305894)

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31 December 2019

title

Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway (English)

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31 December 2019

0 references

1 reference

GOA release 2020-03-11

positive regulation of sodium ion transmembrane transporter activity

1 reference

GOA release 2020-03-11

0 references

2

1 reference

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31 December 2019

Erwin F Shibata

6

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31 December 2019

author name string

John S Lowe

1

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31 December 2019

Naina Bhasin

3

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31 December 2019

Thomas J Hund

4

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31 December 2019

Penelope A Boyden

5

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31 December 2019

Mark E Anderson

7

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31 December 2019

Peter J Mohler

8

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31 December 2019

language of work or name

English

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publication date

7 January 2008

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31 December 2019

published in

Journal of Cell Biology

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31 December 2019

volume

180

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31 December 2019

issue

1

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31 December 2019

page(s)

173-186

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Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes

31 December 2019

cites work

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Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles

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Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

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Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2

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AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

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Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPase alpha subunit

19 March 2017

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The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes

19 March 2017

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19 March 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Ankyrin-G regulates inactivation gating of the neuronal sodium channel, Nav1.6.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Expression of distinct ERG proteins in rat, mouse, and human heart. Relation to functional I(Kr) channels.

27 September 2017

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Sodium channel defects in myotonia and periodic paralysis

27 September 2017

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Immunolocalization of sarcolemmal dihydropyridine receptor and sarcoplasmic reticular triadin and ryanodine receptor in rabbit ventricle and atrium

27 September 2017

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Molecular architecture of membranes involved in excitation-contraction coupling of cardiac muscle

27 September 2017

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Molecular cloning of a putative tetrodotoxin-resistant rat heart Na+ channel isoform

27 September 2017

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Distribution of the Na(+)-Ca2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study

27 September 2017

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27 September 2017

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27 September 2017

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The newborn rabbit sino-atrial node expresses a neuronal type I-like Na+ channel.

30 May 2018

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Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes.

30 May 2018

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A targeting motif involved in sodium channel clustering at the axonal initial segment.

30 May 2018

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New KCNQ1 mutations leading to haploinsufficiency in a general population; Defective trafficking of a KvLQT1 mutant.

21 January 2018

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21 January 2018

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New mechanism contributing to drug-induced arrhythmia: rescue of a misprocessed LQT3 mutant

21 January 2018

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Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart.

21 January 2018

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Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

21 January 2018

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The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

21 January 2018

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KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart

21 January 2018

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The molecular architecture of calcium microdomains in rat cardiomyocytes.

21 January 2018

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Differential expression of voltage-gated K+ channel subunits in adult rat heart. Relation to functional K+ channels?

29 November 2018

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12 December 2020

Trafficking-competent and trafficking-defective KCNJ2 mutations in Andersen syndrome

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12 December 2020

T-tubule localization of the inward-rectifier K(+) channel in mouse ventricular myocytes: a role in K(+) accumulation

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12 December 2020

Catecholaminergic Polymorphic Ventricular Tachycardia

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12 December 2020

Brugada syndrome and sudden death

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12 December 2020

Immunocytochemical localization of rH1 sodium channel in adult rat heart atria and ventricle. Presence in terminal intercalated disks

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12 December 2020

Differential distribution of Kir2.1 and Kir2.3 subunits in canine atrium and ventricle

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12 December 2020

Identifiers

DOI

10.1083/JCB.200710107

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180363%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180363%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

2 references