Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma (Q24301662)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20203100%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma (English)

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19 January 2020

1

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19 January 2020

author name string

Dariusz Martynowski

2

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19 January 2020

Songyang Zheng

3

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19 January 2020

Taira Wada

4

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19 January 2020

Wen Xie

5

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19 January 2020

Yong Li

6

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19 January 2020

language of work or name

English

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publication date

4 March 2010

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19 January 2020

published in

Molecular Endocrinology

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19 January 2020

volume

24

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19 January 2020

issue

5

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19 January 2020

page(s)

923-929

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Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

19 March 2017

1 reference

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

19 March 2017

1 reference

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All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

19 March 2017

1 reference

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Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

19 March 2017

1 reference

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Coot: model-building tools for molecular graphics

19 March 2017

1 reference

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Requirement for RORgamma in thymocyte survival and lymphoid organ development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Nuclear receptors and lipid physiology: opening the X-files

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Processing of X-ray diffraction data collected in oscillation mode

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation.

27 September 2017

1 reference

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Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.

27 September 2017

1 reference

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Orphan nuclear receptors adopted by crystallography

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Ligand control of coregulator recruitment to nuclear receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Activation of nuclear receptors: a perspective from structural genomics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Oxysterols: modulators of cholesterol metabolism and other processes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Orphan nuclear receptors: shifting endocrinology into reverse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2870936

Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20203100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/ME.2009-0507

2 references

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19 January 2020

1 reference

2 references

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19 January 2020

2 references