Alpha-actinin associates with polycystin-2 and regulates its channel activity (Q24300429)

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11 January 2020

title

Alpha-actinin associates with polycystin-2 and regulates its channel activity (English)

1 reference

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Polycystin 2, transient receptor potential cation channel

11 January 2020

main subject

1 reference

GOA release 2020-03-11

actinin binding

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Polycystin 2, transient receptor potential cation channel

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Nicolas Montalbetti

2

1 reference

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11 January 2020

author name string

Qiang Li

1

1 reference

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11 January 2020

Patrick Y Shen

3

1 reference

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11 January 2020

Xiao-Qing Dai

4

1 reference

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11 January 2020

Christopher I Cheeseman

5

1 reference

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11 January 2020

Edward Karpinski

6

1 reference

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11 January 2020

Guanqing Wu

7

1 reference

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11 January 2020

Horacio F Cantiello

8

1 reference

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11 January 2020

Xing-Zhen Chen

9

1 reference

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11 January 2020

language of work or name

English

0 references

publication date

20 April 2005

1 reference

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11 January 2020

published in

Human Molecular Genetics

1 reference

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11 January 2020

volume

14

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11 January 2020

issue

12

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11 January 2020

page(s)

1587-1603

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PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

11 January 2020

cites work

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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

21 January 2018

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Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel

21 January 2018

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Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

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Specific association of the gene product of PKD2 with the TRPC1 channel

21 January 2018

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PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles

21 January 2018

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The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton

21 January 2018

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Polycystin-2 interacts with troponin I, an angiogenesis inhibitor

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Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.

21 January 2018

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The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actinin

21 January 2018

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Competitive binding of alpha-actinin and calmodulin to the NMDA receptor

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The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells

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Regulation of the cardiac L-type Ca2+ channel by the actin-binding proteins alpha-actinin and dystrophin

21 January 2018

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Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle

21 January 2018

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Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

21 January 2018

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Left-Right Asymmetry: Nodal Cilia Make and Catch a Wave

21 January 2018

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Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

21 January 2018

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Human skeletal muscle-specific alpha-actinin-2 and -3 isoforms form homodimers and heterodimers in vitro and in vivo

21 January 2018

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7 January 2021

The alpha-actinin gene family: a revised classification.

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Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

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7 January 2021

Altered distribution and co-localization of polycystin-2 with polycystin-1 in MDCK cells after wounding stress

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7 January 2021

alpha-actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells

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7 January 2021

Polycystin-2 associates with tropomyosin-1, an actin microfilament component

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7 January 2021

Somatic inactivation of Pkd2 results in polycystic kidney disease

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7 January 2021

Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation

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7 January 2021

Focal adhesions - the cytoskeletal connection

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7 January 2021

Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells

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7 January 2021

Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene

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7 January 2021

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

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7 January 2021

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

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7 January 2021

PKD1 interacts with PKD2 through a probable coiled-coil domain

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7 January 2021

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

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7 January 2021

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation

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7 January 2021

Phosphoinositides differentially regulate alpha-actinin flexibility and function

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7 January 2021

New insights into the molecular pathophysiology of polycystic kidney disease

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7 January 2021

Identification and characterization of polycystin-2, the PKD2 gene product

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7 January 2021

CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4

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7 January 2021

In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2

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7 January 2021

Analysis of the alpha-actinin/zyxin interaction

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7 January 2021

Voltage dependence and pH regulation of human polycystin-2-mediated cation channel activity

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7 January 2021

Polycystin-1 interacts with intermediate filaments

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7 January 2021

ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions

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7 January 2021

Polycystin-1 activates and stabilizes the polycystin-2 channel.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Distinct subcellular expression of endogenous polycystin-2 in the plasma membrane and Golgi apparatus of MDCK cells

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7 January 2021

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7 January 2021

Molecular basis of polycystic kidney disease: PKD1, PKD2 and PKHD1.

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7 January 2021

Genetics and pathogenesis of polycystic kidney disease.

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7 January 2021

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

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7 January 2021

Regulation of single NMDA receptor channel activity by alpha-actinin and calmodulin in rat hippocampal granule cells

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7 January 2021

Cytoskeletal regulation of calcium-permeable cation channels in the human syncytiotrophoblast: role of gelsolin

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7 January 2021

Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia

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7 January 2021

Identification and localization of polycystin, the PKD1 gene product

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7 January 2021

Interactions of calmodulin and alpha-actinin with the NR1 subunit modulate Ca2+-dependent inactivation of NMDA receptors

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7 January 2021