Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease (Q24299645)

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English	Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease	scientific article

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scholarly article

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Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease (English)

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Parkinson's disease

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based on heuristic

inferred from title

Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

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GOA release 2020-03-11

Synuclein, alpha

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GOA release 2020-03-11

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Maria Grazia Spillantini

7

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Arianna Bellucci

object named as

Arianna Bellucci

1

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PierFranco Spano

object named as

Pierfranco Spano

10

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author name string

Laura Navarria

2

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Elisa Falarti

3

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Michela Zaltieri

4

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Federica Bono

5

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Ginetta Collo

6

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Maria Grazia

8

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Cristina Missale

9

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language of work or name

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publication date

2011

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6

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e27959

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12

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copyright license

Creative Commons Attribution 4.0 International

7 December 2011

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April 2022 Public Data File from Crossref

copyright status

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Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

1 reference

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Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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Alpha-synuclein in Lewy bodies

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Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

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α-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter.

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Synuclein modulation of monoamine transporters

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Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease.

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Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine

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Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons.

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SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease

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Dopamine transporter trafficking: rapid response on demand

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Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges.

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27 September 2017

Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells

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27 September 2017

Rab 11 regulates constitutive dopamine transporter trafficking and function in N2A neuroblastoma cells

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27 September 2017

{alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics

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27 September 2017

Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway

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Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors.

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27 September 2017

Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation

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Physiological and pathological properties of alpha-synuclein

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Cell systems and the toxic mechanism(s) of alpha-synuclein

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D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism.

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RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport.

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27 September 2017

Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter

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27 September 2017

The biochemistry of Parkinson's disease

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A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease

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27 September 2017

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

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27 September 2017

Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein

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Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists.

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DAncing past the DAT at a DA synapse

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Comparative analyses of alpha-synuclein expression levels in rat brain tissues and transfected cells

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27 September 2017

Mutations in the lipid-binding domain of α-synuclein confer overlapping, yet distinct, functional properties in the regulation of dopamine transporter activity

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27 September 2017

Attenuation of dopamine transporter activity by alpha-synuclein

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27 September 2017

Cocaine increases dopamine uptake and cell surface expression of dopamine transporters

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Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

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27 September 2017

The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease

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Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter

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alpha-Synuclein pathology in the neostriatum in Parkinson's disease

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12 December 2020

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10.1371/JOURNAL.PONE.0027959

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2011PLoSO...627959B

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