IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation (Q24298339)

Tripat Kaur Oberoi

Dagmar Meyer zu Heringdorf

1

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Dagmar Meyer zu Heringdorf

8

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Reinhard W. Köster

Reinhard W Köster

15

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Boris Macek

Boris Macek

14

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author name string

Taner Dogan

2

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Jennifer C Hocking

3

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Rolf-Peter Scholz

4

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Juliane Mooz

5

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Carrie L Anderson

6

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Christiaan Karreman

7

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Gudula Schmidt

9

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Mika Ruonala

10

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Kazuhiko Namikawa

11

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Gregory S Harms

12

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Alejandro Carpy

13

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Krishnaraj Rajalingam

Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription

16

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language of work or name

English

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publication date

4 January 2012

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published in

The EMBO Journal

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volume

31

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page(s)

14-28

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issue

1

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cites work

1 reference

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IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

19 March 2017

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cIAP1 Localizes to the nuclear compartment and modulates the cell cycle

19 March 2017

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CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration

19 March 2017

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19 March 2017

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X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

19 March 2017

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7 April 2017

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SUMOylation of the GTPase Rac1 is required for optimal cell migration

27 September 2017

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27 September 2017

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IAP regulation of metastasis

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The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2.

27 September 2017

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Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

27 September 2017

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27 September 2017

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IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

27 September 2017

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(Un)expected roles of c-IAPs in apoptotic and NFkappaB signaling pathways

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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29 November 2018

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The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22117219

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2011.423

1 reference

release_d4wp3hwtd5fobleztolovunqbi

3419484

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d4wp3hwtd5fobleztolovunqbi

mapped directly with Wikidata item

24 November 2022

based on heuristic

3419484

1 reference

1 reference

1 reference