Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6 (Q24293466)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

Cyclin dependent kinase 6

8 February 2020

main subject

1 reference

type B pancreatic cell development

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Irene Cózar-Castellano

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Nathalie M Fiaschi-Taesch

1

1 reference

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8 February 2020

Fatimah Salim

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jeffrey Kleinberger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ronnie Troxell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Karen Selk

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Edward Cherok

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Karen K Takane

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Donald K Scott

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Andrew F Stewart

10

1 reference

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8 February 2020

language of work or name

English

0 references

publication date

1 August 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

8

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8 February 2020

page(s)

1926-1936

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

8 February 2020

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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7 April 2017

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Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note.

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Cyclin D2 protein stability is regulated in pancreatic beta-cells

27 September 2017

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The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells

27 September 2017

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Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.

27 September 2017

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27 September 2017

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Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo

27 September 2017

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Glycogen synthase kinase-3 and mammalian target of rapamycin pathways contribute to DNA synthesis, cell cycle progression, and proliferation in human islets

27 September 2017

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Beta-cell proliferation, but not neogenesis, following 60% partial pancreatectomy is impaired in the absence of FoxM1.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Partial pancreatectomy in adult humans does not provoke beta-cell regeneration

29 November 2018

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Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.

29 November 2018

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29 November 2018

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Overexpression of cyclin D1 in pancreatic beta-cells in vivo results in islet hyperplasia without hypoglycemia.

29 November 2018

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Mouse development and cell proliferation in the absence of D-cyclins.

29 November 2018

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Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

29 November 2018

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Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911074

Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

29 November 2018

1 reference

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Experimental transplantation of human fetal and adult pancreatic islets

29 November 2018

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A SELECTIVE DECREASE IN THE BETA CELL MASS OF HUMAN ISLETS TRANSPLANTED INTO DIABETIC NUDE MICE

29 November 2018

1 reference

12 December 2020

Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro

1 reference

12 December 2020

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

1 reference

12 December 2020

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy

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12 December 2020

Overexpression of cyclin D1 occurs frequently in human pancreatic endocrine tumors

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12 December 2020

Identifiers

DOI

10.2337/DB09-1776

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668294%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference