Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein (Q24290359)

insulin receptor signaling pathway

GOA release 2020-03-11

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GOA release 2020-03-11

PH-interacting protein

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GOA release 2020-03-11

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J Farhang-Fallah

1

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X Yin

2

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G Trentin

3

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A M Cheng

4

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M Rozakis-Adcock

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

22 December 2000

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published in

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volume

275

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page(s)

40492-7

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issue

51

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cites work

The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Heterologous pleckstrin homology domains do not couple IRS-1 to the insulin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

IRS pleckstrin homology domains bind to acidic motifs in proteins

21 January 2018

1 reference

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

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Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

21 January 2018

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A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

21 January 2018

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Oncogene ect2 is related to regulators of small GTP-binding proteins

21 January 2018

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The bromodomain revisited.

21 January 2018

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Phosphorylated CREB binds specifically to the nuclear protein CBP

21 January 2018

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Role of IRS-1-GRB-2 complexes in insulin signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.C000611200

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

21 January 2018

1 reference

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Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin

21 January 2018

1 reference

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The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis

21 January 2018

1 reference

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Specific role for the PH domain of dynamin-1 in the regulation of rapid endocytosis in adrenal chromaffin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000611200

Pleckstrin associates with plasma membranes and induces the formation of membrane projections: requirements for phosphorylation and the NH2-terminal PH domain

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.C000611200

1 reference

Consolidated OpenCitations Corpus – April 2017

945808

945808

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference