Systems biology and biomarkers of early effects for occupational exposure limit setting (Q23911416)

DART

1 reference

NIOSH Division of Science Integration

25 September 2023

EID

1 reference

25 September 2023

1 reference

19 July 2017

1 reference

29 March 2020

environmental monitoring

1 reference

dose–response relationship

29 March 2020

1 reference

occupational exposure limit

29 March 2020

1 reference

29 March 2020

1 reference

29 March 2020

1 reference

29 March 2020

1 reference

29 March 2020

8

0 references

Lynne T. Haber

Lynne T Haber

4

0 references

Lyle D. Burgoon

Lyle Burgoon

2

0 references

author name string

D Gayle DeBord

1

0 references

Stephen W Edwards

3

0 references

M Helen Kanitz

5

0 references

Eileen Kuempel

6

0 references

Russell S Thomas

Journal of Occupational and Environmental Hygiene

7

0 references

language of work or name

English

0 references

publication date

2015

0 references

published in

1 reference

8 December 2019

12 Suppl 1

0 references

issue

sup1

0 references

page(s)

S41-54

0 references

performing organization

Taylor & Francis

Taylor & Francis Group, LLC

1 reference

on focus list of Wikimedia project

2 February 2024

Wikimedia–NIOSH collaboration

0 references

1 reference

25 September 2023

Toxicogenomic profiling of chemically exposed humans in risk assessment

2 references

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Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

KEGG for representation and analysis of molecular networks involving diseases and drugs

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

A statistical model for assessing genetic susceptibility as a risk factor in multifactorial diseases: lessons from occupational asthma

19 March 2017

2 references

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Methodologic issues in using epidemiologic studies of occupational cohorts for cancer risk assessment

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

A Bayesian network model for biomarker-based dose response

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Differential lung inflammation and injury with tobacco smoke exposure in Wistar Kyoto and spontaneously hypertensive rats

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Assessing biomarker use in risk assessment - A survey of practitioners

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

DNA methylation in cancer: a gene silencing mechanism and the clinical potential of its biomarkers

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

IPCS framework for analyzing the relevance of a noncancer mode of action for humans

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Epigenetic Regulation in Particulate Matter-Mediated Cardiopulmonary Toxicities: A Systems Biology Perspective

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Modification by ALAD of the association between blood lead and blood pressure in the U.S. population: results from the Third National Health and Nutrition Examination Survey

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Fundamental carcinogenic processes and their implications for low dose risk assessment

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Rat- and human-based risk estimates of lung cancer from occupational exposure to poorly-soluble particles: a quantitative evaluation

19 March 2017

1 reference

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Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology

22 April 2017

1 reference

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Computational systems biology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Exploring the new world of the genome with DNA microarrays

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Systems biology of human epilepsy applied to patients with brain tumors.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Advancing the next generation of health risk assessment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Informing selection of nanomaterial concentrations for ToxCast in vitro testing based on occupational exposure potential

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Biomonitoring-based risk assessment for hexabromocyclododecane (HBCD).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Quantitative knowledge-based analysis in compound safety assessment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Linear low-dose extrapolation for noncancer heath effects is the exception, not the rule.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

New directions in toxicity testing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

SAR/QSAR methods in public health practice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Endocrine profiling and prioritization of environmental chemicals using ToxCast data

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

An animal protection perspective on 21st century toxicology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Systems biology: an approach.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Interpreting NHANES biomonitoring data, cadmium

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

What role for biologically based dose-response models in estimating low-dose risk?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Molecular networks as sensors and drivers of common human diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

State-of-the-science workshop report: issues and approaches in low-dose-response extrapolation for environmental health risk assessment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Toxicity testing in the 21st century: bringing the vision to life

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Metabolic syndrome: from epidemiology to systems biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Evidence-based dose-response assessment for thyroid tumorigenesis from acrylamide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Applications of metabolomics in drug discovery and development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Dose response considerations in risk assessment--an overview of recent ILSI activities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Guidelines for the derivation of Biomonitoring Equivalents: report from the Biomonitoring Equivalents Expert Workshop

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Novel technologies for the discovery and quantitation of biomarkers of toxicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Metabolomics: a global biochemical approach to drug response and disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Computational toxicology--a state of the science mini review

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

BMDExpress: a software tool for the benchmark dose analyses of genomic data

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Genotoxicity of poorly soluble particles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

Estimating risk from ambient concentrations of acrolein across the United States.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

The ToxCast program for prioritizing toxicity testing of environmental chemicals

27 September 2017

1 reference

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New directions in incidence-dose modeling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

The Benchmark Dose Method—Review of Available Models, and Recommendations for Application in Health Risk Assessment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654673

The use of biologically based modeling in risk assessment

27 September 2017

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Differential sensitivity of children and adults to chemical toxicity. II. Risk and regulation

27 September 2017

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Time extrapolation and interspecies extrapolation for locally acting substances in case of limited toxicological data

27 September 2017

1 reference

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Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies

27 September 2017

1 reference

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Susceptibility differences in chemical carcinogenesis linearize the dose-response relationship: threshold doses can be defined only for individuals

27 September 2017

1 reference

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Harmonization of cancer and noncancer risk assessment: proceedings of a consensus-building workshop

27 September 2017

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Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: criteria, validation, strategies

27 September 2017

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Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells

27 September 2017

1 reference

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Cross-species comparisons of transcriptomic alterations in human and rat primary hepatocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

27 September 2017

1 reference

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Application of transcriptional benchmark dose values in quantitative cancer and noncancer risk assessment

30 May 2018

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Computational toxicology: realizing the promise of the toxicity testing in the 21st century

30 May 2018

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Systems biology and mode of action based risk assessment

30 May 2018

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Temporal concordance between apical and transcriptional points of departure for chemical risk assessment.

21 January 2018

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Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment

21 January 2018

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Virtual tissues in toxicology

21 January 2018

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Computational systems biology and dose-response modeling in relation to new directions in toxicity testing.

21 January 2018

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Biomarkers in toxicology and risk assessment

21 January 2018

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Future of toxicogenomics and safety signatures: balancing public access to data with proprietary drug discovery

21 January 2018

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Nanotoxicology: in vitro-in vivo dosimetry

21 January 2018

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A new method for determining allowable daily intakes.

21 January 2018

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A comprehensive statistical analysis of predicting in vivo hazard using high-throughput in vitro screening

21 January 2018

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Human and rat primary hepatocyte CYP1A1 and 1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran, and 2,3,4,7,8-pentachlorodibenzofuran.

21 January 2018

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Pneumoconiosis-related lung cancers: preferential occurrence from diffuse interstitial fibrosis-type pneumoconiosis

21 January 2018

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12 December 2020

Statistical design and the analysis of gene expression microarray data

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12 December 2020

Human variability and noncancer risk assessment- An analysis of the default uncertainty factor

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12 December 2020

Human interindividual variability--a major source of uncertainty in assessing risks for noncancer health effects

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12 December 2020

Human biomonitoring as a pragmatic tool to support health risk management of chemicals--examples under the EU REACH programme

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12 December 2020

Epidemiology and risk assessment

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12 December 2020

Empowering microarrays in the regulatory setting

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12 December 2020

Distributions of individual susceptibility among humans for toxic effects. How much protection does the traditional tenfold factor provide for what fraction of which kinds of chemicals and effects?

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12 December 2020

Biological markers in environmental health research. Committee on Biological Markers of the National Research Council

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