Phosphoglycerate kinase 1 (Q21156424)

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mammalian protein found in Homo sapiens

cell migration-inducing gene 10 protein
PRP 2
PGK1
primer recognition protein 2
epididymis secretory sperm binding protein Li 68p
phosphoglycerate kinase 1

Language	Label	Description	Also known as
English	Phosphoglycerate kinase 1	mammalian protein found in Homo sapiens	cell migration-inducing gene 10 protein PRP 2 PGK1 primer recognition protein 2 epididymis secretory sperm binding protein Li 68p phosphoglycerate kinase 1

Statements

1 reference

13 November 2019

UniProt protein ID

phosphoglycerate kinase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00558

Phosphoglycerate kinase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00558

Phosphoglycerate kinase superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00558

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Phosphoglycerate kinase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

protein binding

determination method

2 references

8 April 2019

Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy in living cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

phosphoglycerate kinase activity

determination method

6 references

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

protein-disulfide reductase (NAD(P)) activity

determination method

1 reference

8 April 2019

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

phosphoglycerate kinase activity

determination method

7 references

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

1 January 2018

A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

1 January 2018

Human phosphoglycerate kinase. I. Crystallization and characterization of normal enzyme

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

phosphoglycerate kinase activity

determination method

6 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

determination method

1 reference

8 April 2019

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

extracellular exosome

determination method

5 references

17 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

determination method

1 reference

17 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

extracellular space

determination method

1 reference

8 April 2019

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

determination method

1 reference

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

extracellular exosome

determination method

4 references

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

biological process

gluconeogenesis

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

epithelial cell differentiation

determination method

1 reference

8 April 2019

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

canonical glycolysis

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

glycolytic process

determination method

4 references

17 October 2017

A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

negative regulation of angiogenesis

determination method

1 reference

8 April 2019

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

plasminogen activation

determination method

1 reference

8 April 2019

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

cellular response to hypoxia

determination method

1 reference

8 April 2019

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

response to hypoxia

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

glycolytic process

determination method

5 references

8 April 2019

A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

chemical synaptic transmission

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

myoblast fusion

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

somatic muscle development

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

epithelial cell differentiation

determination method

muscle cell cellular homeostasis

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00558&geneProductId=UniProtKB:P00558

determination method

positive regulation of oxidative phosphorylation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00558

determination method

Phosphoglycerate kinase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00558

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000362413

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000362413

ENSP00000496140

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496140

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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