A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci (Q21145042)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

genome-wide association study

4 January 2020

main subject

0 references

1 reference

1 reference

13

Jane Worthington

Jane

Worthington

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

7

Carol Wise

Carol

Wise

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

15

Pui-Yan Kwok

Pui-Yan

Kwok

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

14

Ian Bruce

Ian

Bruce

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

20

Anne M Bowcock

Anne M

Bowcock

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

18

Anne Barton

Anne

Barton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

3

Wilson Liao

Wilson

Liao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

17

James Krueger

James

Krueger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

5

Shenghui

Duan

Shenghui Duan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

16

Alan

Menter

Alan Menter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

2

Cynthia

Helms

Cynthia Helms

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

10

Clive R

Pullinger

Clive R Pullinger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Ying Liu

1

Ying

Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Lisa C Zaba

4

Lisa C

Zaba

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Jennifer Gardner

6

Jennifer

Gardner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Andrew Miner

8

Andrew

Miner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

M J Malloy

9

M J

Malloy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

John P Kane

11

John P

Kane

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Scott Saccone

12

Scott

Saccone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Nancy L Saccone

19

Nancy L

Saccone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

28 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

e1000041

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

4 January 2020

copyright license

1 reference

0 references

describes a project that uses

genome-wide association study

1 reference

PLINK: a tool set for whole-genome association and population-based linkage analyses

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

European population substructure: clustering of northern and southern populations

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Genetic epidemiology of psoriasis and psoriatic arthritis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

The binary interacting network of the conserved oligomeric Golgi tethering complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Inference of population structure using multilocus genotype data

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Principal components analysis corrects for stratification in genome-wide association studies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Granulysin: a novel host defense molecule

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Human ADAM33: protein maturation and localization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Calmin, a protein with calponin homology and transmembrane domains expressed in maturing spermatogenic cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

New models of collaboration in genome-wide association studies: the Genetic Association Information Network

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

A whole-genome association study of major determinants for host control of HIV-1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

ADAM33, a new candidate for psoriasis susceptibility

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

HLA-Cw6 and HLA-DRB1*07 together are associated with less severe joint disease in psoriatic arthritis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Psoriasis: genetic associations and immune system changes.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Psoriatic arthritis: one or more diseases?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Getting under the skin: the immunogenetics of psoriasis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

The New York Cancer Project: rationale, organization, design, and baseline characteristics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Genomic control, a new approach to genetic-based association studies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

A test for linkage and association in general pedigrees: the pedigree disequilibrium test

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Use of unlinked genetic markers to detect population stratification in association studies.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Immunologic mechanisms in psoriasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2274885

HLA is a candidate region for psoriatic arthritis. evidence for excessive HLA sharing in sibling pairs.

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Expression of Catenin family members CTNNA1, CTNNA2, CTNNB1 and JUP in the primate prefrontal cortex and hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

Fine Mapping of the PSORS4 Psoriasis Susceptibility Region on Chromosome 1q21

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

The genetics of psoriasis: a complex disorder of the skin and immune system

21 January 2018

1 reference

12 December 2020

Psoriasis Genetics: The Way Forward

1 reference

12 December 2020

Psoriasis and HLA-Cw6

1 reference

12 December 2020

Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy

1 reference

12 December 2020

Variants in the 5q31 cytokine gene cluster are associated with psoriasis

1 reference

12 December 2020

Recurrence risk for psoriasis and psoriatic arthritis within sibships

1 reference

12 December 2020

Pathogenesis of psoriatic arthritis

1 reference

12 December 2020

Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis

1 reference

12 December 2020

Tests for Linear Trends in Proportions and Frequencies

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000041

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1371/JOURNAL.PGEN.1000041

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18369459%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

2 references