Splicing factor 1 (Q21132948)

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mammalian protein found in Homo sapiens

BBP
transcription factor ZFM1
mammalian branch point-binding protein
splicing factor 1
zinc finger gene in MEN1 locus
zinc finger protein 162
mBBP
SF1

Language	Label	Description	Also known as
English	Splicing factor 1	mammalian protein found in Homo sapiens	BBP transcription factor ZFM1 mammalian branch point-binding protein splicing factor 1 zinc finger gene in MEN1 locus zinc finger protein 162 mBBP SF1

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15637

K Homology domain, type 1 superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15637

Zinc finger, CCHC-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

K Homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

K Homology domain, type 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

Splicing factor 1, helix-hairpin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transcription corepressor activity

determination method

1 reference

9 May 2019

The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

zinc ion binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

metal ion binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

protein binding

determination method

9 references

9 May 2019

Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

U2AF-homology motif interactions are required for alternative splicing regulation by SPF45

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Dynamic protein-protein interaction wiring of the human spliceosome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Structure of Phosphorylated SF1 Bound to U2AF65 in an Essential Splicing Factor Complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

nucleic acid binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

pre-mRNA branch point binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

determination method

6 references

17 October 2017

Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

17 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

determination method

6 references

8 April 2019

Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

determination method

7 references

9 May 2019

Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

determination method

1 reference

9 May 2019

Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

determination method

3 references

9 May 2019

Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

biological process

negative regulation of smooth muscle cell proliferation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

regulation of transcription, DNA-templated

determination method

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

Leydig cell differentiation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

mRNA processing

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

regulation of steroid biosynthetic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

male sex determination

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

transcription, DNA-templated

determination method

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15637&geneProductId=UniProtKB:Q15637

determination method

spliceosomal complex assembly

determination method

1 reference

9 May 2019

Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

mRNA 3'-splice site recognition

determination method

1 reference

9 May 2019

Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

negative regulation of nucleic acid-templated transcription

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

mRNA splicing, via spliceosome

determination method

nuclear body organization

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15637

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

4 April 2020

1 reference

4 April 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000227503

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000227503

ENSP00000334414

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000334414

ENSP00000366604

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000366604

ENSP00000366607

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000366607

ENSP00000366611

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000366611

ENSP00000396793

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000396793

ENSP00000388470

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000388470

ENSP00000391198

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000391198

ENSP00000395927

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395927

ENSP00000406354

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000406354

ENSP00000407962

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000407962

ENSP00000419062

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000419062

ENSP00000486693

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486693

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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