Transformer 2 beta homolog (Q21122214)

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mammalian protein found in Homo sapiens

splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)
transformer-2 protein homolog B
TRA2B
transformer-2 protein homolog beta
protein phosphatase 1, regulatory subunit 156
Splicing factor, arginine/serine-rich 10
TRA-2 beta

Language	Label	Description	Also known as
English	Transformer 2 beta homolog	mammalian protein found in Homo sapiens	splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) transformer-2 protein homolog B TRA2B transformer-2 protein homolog beta protein phosphatase 1, regulatory subunit 156 Splicing factor, arginine/serine-rich 10 TRA-2 beta

Statements

1 reference

13 November 2019

UniProt protein ID

RNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62995

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62995

RNA recognition motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleic acid binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

protein binding

determination method

8 references

8 April 2019

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

The protein interaction landscape of the human CMGC kinase group

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Dynamic protein-protein interaction wiring of the human spliceosome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

poly-purine tract binding

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

determination method

4 references

26 September 2017

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

protein domain specific binding

determination method

1 reference

8 April 2019

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

identical protein binding

determination method

1 reference

8 April 2019

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

determination method

5 references

8 April 2019

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

pre-mRNA binding

determination method

1 reference

8 April 2019

Regulation of RAGE splicing by hnRNP A1 and Tra2β-1 and its potential role in AD pathogenesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

determination method

6 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

26 September 2017

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

nuclear inner membrane

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

spliceosomal complex

determination method

1 reference

26 September 2017

Regulation of RAGE splicing by hnRNP A1 and Tra2β-1 and its potential role in AD pathogenesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

determination method

6 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

ribonucleoprotein complex

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

biological process

RNA splicing, via transesterification reactions

determination method

1 reference

8 April 2019

Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

cerebral cortex regionalization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

mRNA processing

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

negative regulation of mRNA splicing, via spliceosome

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62995&geneProductId=UniProtKB:P62995

determination method

embryonic brain development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

regulation of alternative mRNA splicing, via spliceosome

determination method

3 references

8 April 2019

Regulation of RAGE splicing by hnRNP A1 and Tra2β-1 and its potential role in AD pathogenesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

regulation of RNA splicing

determination method

1 reference

8 April 2019

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

protein complex oligomerization

determination method

1 reference

8 April 2019

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

cellular response to glucose stimulus

determination method

1 reference

8 April 2019

Regulation of RAGE splicing by hnRNP A1 and Tra2β-1 and its potential role in AD pathogenesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

positive regulation of mRNA splicing, via spliceosome

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62995

determination method

RNA recognition motif domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62995

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000343857

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000343857

ENSP00000371626

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000371626

ENSP00000416887

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000416887

ENSP00000416959

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000416959

ENSP00000259043

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000259043

ENSP00000406561

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000406561

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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