General transcription factor IIH subunit 4 (Q21122192)

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mammalian protein found in Homo sapiens

general transcription factor IIH polypeptide 4
BTF2 p52
general transcription factor IIH, polypeptide 4, 52kDa
basic transcription factor 2 52 kDa subunit
GTF2H4
general transcription factor IIH subunit 4
TFIIH basal transcription factor complex p52 subunit

Language	Label	Description	Also known as
English	General transcription factor IIH subunit 4	mammalian protein found in Homo sapiens	general transcription factor IIH polypeptide 4 BTF2 p52 general transcription factor IIH, polypeptide 4, 52kDa basic transcription factor 2 52 kDa subunit GTF2H4 general transcription factor IIH subunit 4 TFIIH basal transcription factor complex p52 subunit

Statements

1 reference

13 November 2019

UniProt protein ID

Transcription factor TFIIH subunit p52/Tfb2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q92759

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein kinase activity

determination method

1 reference

8 April 2019

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

ATP-dependent activity, acting on DNA

determination method

1 reference

8 April 2019

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

DNA-binding transcription factor activity

determination method

1 reference

10 September 2018

Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

DNA helicase activity

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

protein binding

determination method

3 references

8 April 2019

Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

8 April 2019

Structural basis for group A trichothiodystrophy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

RNA polymerase II CTD heptapeptide repeat kinase activity

determination method

1 reference

16 July 2018

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

double-stranded DNA binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

ATPase activator activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

RNA polymerase II CTD heptapeptide repeat kinase activity

determination method

RNA polymerase II general transcription initiation factor activity

determination method

1 reference

8 April 2019

Near-atomic resolution visualization of human transcription promoter opening

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription factor TFIIH holo complex

determination method

1 reference

16 July 2018

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

core TFIIH complex portion of holo TFIIH complex

determination method

1 reference

8 April 2019

Near-atomic resolution visualization of human transcription promoter opening

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription factor TFIIH core complex

determination method

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

transcription factor TFIID complex

determination method

1 reference

8 April 2019

Near-atomic resolution visualization of human transcription promoter opening

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription factor TFIIH holo complex

determination method

biological process

termination of RNA polymerase I transcription

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

regulation of transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

phosphorylation of RNA polymerase II C-terminal domain

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription initiation from RNA polymerase I promoter

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription elongation from RNA polymerase II promoter

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

7-methylguanosine mRNA capping

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription by RNA polymerase II

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

8 April 2019

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

8 April 2019

Near-atomic resolution visualization of human transcription promoter opening

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription, DNA-templated

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

cellular response to DNA damage stimulus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

global genome nucleotide-excision repair

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription-coupled nucleotide-excision repair

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription initiation from RNA polymerase II promoter

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

nucleotide-excision repair, DNA incision

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

nucleotide-excision repair, preincision complex stabilization

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

nucleotide-excision repair, preincision complex assembly

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

nucleotide-excision repair, DNA incision, 5'-to lesion

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

DNA duplex unwinding

determination method

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92759&geneProductId=UniProtKB:Q92759

determination method

positive regulation of ATP-dependent activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

nucleotide-excision repair, DNA duplex unwinding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

nucleotide-excision repair, DNA incision, 3'-to lesion

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

transcription elongation from RNA polymerase I promoter

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92759

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000259895

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000259895

ENSP00000365493

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000365493

ENSP00000365504

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000365504

ENSP00000383300

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383300

ENSP00000387980

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000387980

ENSP00000388227

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000388227

ENSP00000395497

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395497

ENSP00000396251

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000396251

ENSP00000399554

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000399554

ENSP00000401105

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000401105

ENSP00000403156

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403156

ENSP00000409483

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000409483

ENSP00000389851

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000389851

ENSP00000411553

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411553

ENSP00000394961

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394961

ENSP00000398484

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000398484

ENSP00000397410

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397410

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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