FUS RNA binding protein (Q21118098)

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mammalian protein found in Homo sapiens
  • POMp75
  • fusion gene in myxoid liposarcoma
  • RNA-binding protein FUS
  • FUS
  • FUS/ERG chimeric protein
  • 75 kDa DNA-pairing protein
  • fused in sarcoma
  • translocated in liposarcoma protein
  • oncogene FUS
  • fus-like protein
  • FUS/ERG fusion protein
  • heterogeneous nuclear ribonucleoprotein P2
  • oncogene TLS
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Language Label Description Also known as
English
FUS RNA binding protein
mammalian protein found in Homo sapiens
  • POMp75
  • fusion gene in myxoid liposarcoma
  • RNA-binding protein FUS
  • FUS
  • FUS/ERG chimeric protein
  • 75 kDa DNA-pairing protein
  • fused in sarcoma
  • translocated in liposarcoma protein
  • oncogene FUS
  • fus-like protein
  • FUS/ERG fusion protein
  • heterogeneous nuclear ribonucleoprotein P2
  • oncogene TLS

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
8 April 2019
stated in
FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription
GOA
curator
UniProt
UniProt protein ID
P35637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis and specificity of human otubain 1-mediated deubiquitination
GOA
curator
UniProt
UniProt protein ID
P35637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP
GOA
curator
UniProt
UniProt protein ID
P35637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing
GOA
curator
UniProt
UniProt protein ID
P35637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
Identification of DeltaNp63alpha protein interactions by mass spectrometry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
Fused in sarcoma (FUS) interacts with the cytolinker protein plectin: implications for FUS subcellular localization and function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
retrieved
8 April 2019
stated in
A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IPI
cell component
nucleus
determination method
IBA
IDA
IEA
TAS
7 references
retrieved
8 April 2019
stated in
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IEA
retrieved
8 April 2019
stated in
FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription
GOA
curator
UniProt
UniProt protein ID
P35637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IDA
retrieved
8 April 2019
stated in
Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinases
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IDA
retrieved
8 April 2019
stated in
FUS/TLS is a co-activator of androgen receptor in prostate cancer cells
GOA
curator
Community Assessment of Community Annotation with Ontologies
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35637
determination method
IBA
biological process

Identifiers

 
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