Peroxiredoxin 4 (Q21116097)

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mammalian protein found in Homo sapiens

prx-IV
thioredoxin peroxidase (antioxidant enzyme)
thioredoxin peroxidase AO372
thioredoxin-dependent peroxide reductase A0372
PRDX4
peroxiredoxin-4
AOE37-2
antioxidant enzyme AOE372
epididymis secretory sperm binding protein Li 97n
peroxiredoxin IV

Language	Label	Description	Also known as
English	Peroxiredoxin 4	mammalian protein found in Homo sapiens	prx-IV thioredoxin peroxidase (antioxidant enzyme) thioredoxin peroxidase AO372 thioredoxin-dependent peroxide reductase A0372 PRDX4 peroxiredoxin-4 AOE37-2 antioxidant enzyme AOE372 epididymis secretory sperm binding protein Li 97n peroxiredoxin IV

Statements

1 reference

13 November 2019

UniProt protein ID

Thioredoxin-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13162

Peroxiredoxin, AhpC-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13162

Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, protein family

1 reference

based on heuristic

inferred from protein domain or family

Thioredoxin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peroxiredoxin, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein homodimerization activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

peroxidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

thioredoxin peroxidase activity

determination method

1 reference

26 September 2017

Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13162&geneProductId=UniProtKB:Q13162

determination method

protein binding

determination method

3 references

8 April 2019

Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

8 April 2019

Peroxiredoxin-4 interacts with and regulates the thromboxane A(2) receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13162&geneProductId=UniProtKB:Q13162

determination method

smooth endoplasmic reticulum

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13162&geneProductId=UniProtKB:Q13162

determination method

extracellular exosome

determination method

1 reference

26 September 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13162&geneProductId=UniProtKB:Q13162

determination method

determination method

1 reference

26 September 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13162&geneProductId=UniProtKB:Q13162

determination method

extracellular space

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

secretory granule lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

ficolin-1-rich granule lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

extracellular region

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

determination method

1 reference

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

endoplasmic reticulum

determination method

3 references

extracellular exosome

determination method

1 reference

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

biological process

male gonad development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

4-hydroxyproline metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

extracellular matrix organization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

I-kappaB phosphorylation

determination method

1 reference

8 April 2019

Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

protein maturation by protein folding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

reactive oxygen species metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

spermatogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

negative regulation of male germ cell proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

cellular oxidant detoxification

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

neutrophil degranulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

response to oxidative stress

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

hydrogen peroxide catabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13162

determination method

cell redox homeostasis

determination method

Thioredoxin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13162

Peroxiredoxin, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13162

Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13162

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000368646

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000368646

ENSP00000368635

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000368635

ENSP00000368654

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000368654

ENSP00000413736

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000413736

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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