Endothelin 2 (Q21112275)

http://www.ebi.ac.uk/interpro/protein/P20800

Endothelin-like toxin family

1 reference

based on heuristic

inferred from protein domain or family

Endothelin-like toxin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

endothelin B receptor binding

1 reference

8 April 2019

Cloning and functional expression of human cDNA for the ETB endothelin receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

intracellular anatomical structure

IPI

cell component

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20800&geneProductId=UniProtKB:P20800

1 reference

8 April 2019

Ursodeoxycholic acid reduces increased circulating endothelin 2 in primary biliary cirrhosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

positive regulation of prostaglandin-endoperoxide synthase activity

biological process

2 references

8 April 2019

Prostaglandin endoperoxide synthase-2 contributes to the endothelin/sarafotoxin-induced prostaglandin E2 synthesis in mouse osteoblastic cells (MC3T3-E1): evidence for a protein tyrosine kinase-signaling pathway and involvement of protein kinase C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

hormonal regulation of the force of heart contraction

1 reference

8 April 2019

Positive inotropic effect of endothelin-2 on human atrium preparations in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

regulation of systemic arterial blood pressure by endothelin

TAS

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

8 April 2019

Characterization of endothelin receptors in the human umbilical artery and vein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

cytokine-mediated signaling pathway

1 reference

8 April 2019

Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

positive regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

The involvement of protein kinase G in stimulation of neutrophil migration by endothelins

neutrophil chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

positive regulation of heart rate

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

positive regulation of leukocyte chemotaxis

1 reference

8 April 2019

The involvement of protein kinase G in stimulation of neutrophil migration by endothelins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

cell surface receptor signaling pathway

1 reference

8 April 2019

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors

IC

macrophage chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

regulation of vasoconstriction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

positive regulation of cell population proliferation

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

artery smooth muscle contraction

1 reference

8 April 2019

Characterization of endothelin receptors in the human umbilical artery and vein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors

macrophage activation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

prostaglandin biosynthetic process

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

8 April 2019

Prostaglandin endoperoxide synthase-2 contributes to the endothelin/sarafotoxin-induced prostaglandin E2 synthesis in mouse osteoblastic cells (MC3T3-E1): evidence for a protein tyrosine kinase-signaling pathway and involvement of protein kinase C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

lung alveolus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

temperature homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

positive regulation of the force of heart contraction by chemical signal

1 reference

8 April 2019

Positive inotropic effect of endothelin-2 on human atrium preparations in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

inositol phosphate-mediated signaling

TAS

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

positive regulation of smooth muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

calcium-mediated signaling

1 reference

8 April 2019

Effects of endothelins on signal transduction and proliferation in human melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

G protein-coupled receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20800

TAS

has part(s)

Endothelin-like toxin

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20800

Endothelin-like toxin, conserved site

1 reference

stated in

InterPro Release 71.0