Serine/threonine kinase 25 (Q21109159)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

SOK-1
STK25
serine/threonine-protein kinase 25
sterile 20/oxidant stress-response kinase 1
ste20-like kinase
ste20/oxidant stress response kinase 1
Ste20, yeast homolog

Language	Label	Description	Also known as
English	Serine/threonine kinase 25	mammalian protein found in Homo sapiens	SOK-1 STK25 serine/threonine-protein kinase 25 sterile 20/oxidant stress-response kinase 1 ste20-like kinase ste20/oxidant stress response kinase 1 Ste20, yeast homolog

Statements

1 reference

13 November 2019

UniProt protein ID

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00506

Serine/threonine kinase 25, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

protein binding

determination method

14 references

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

Structural basis for the unique heterodimeric assembly between cerebral cavernous malformation 3 and germinal center kinase III

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

determination method

2 references

protein serine/threonine kinase activity

determination method

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

determination method

MAP kinase kinase kinase kinase activity

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

extracellular exosome

determination method

1 reference

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

extracellular exosome

determination method

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

biological process

intrinsic apoptotic signaling pathway in response to hydrogen peroxide

determination method

1 reference

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

phosphorylation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

response to oxidative stress

determination method

1 reference

8 April 2019

Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

positive regulation of axonogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

establishment of Golgi localization

determination method

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

Golgi reassembly

determination method

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

establishment or maintenance of cell polarity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

protein phosphorylation

determination method

3 references

protein autophosphorylation

determination method

1 reference

8 April 2019

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

response to hydrogen peroxide

determination method

1 reference

8 April 2019

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

signal transduction

determination method

1 reference

8 April 2019

Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

positive regulation of stress-activated MAPK cascade

determination method

1 reference

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

determination method

1 reference

17 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

determination method

regulation of mitotic cell cycle

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

determination method

regulation of apoptotic process

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

determination method

neuron projection morphogenesis

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00506&geneProductId=UniProtKB:O00506

determination method

signal transduction

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

stress-activated protein kinase signaling cascade

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

activation of protein kinase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00506

determination method

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00506

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00506

Serine/threonine kinase 25, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00506

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000325748

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000325748

ENSP00000384162

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384162

ENSP00000384444

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384444

ENSP00000385541

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000385541

ENSP00000385687

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000385687

ENSP00000444886

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000444886

ENSP00000446008

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000446008

ENSP00000395104

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395104

ENSP00000399212

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000399212

ENSP00000401114

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000401114

ENSP00000403607

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403607

ENSP00000403866

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403866

ENSP00000404469

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000404469

ENSP00000404552

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000404552

ENSP00000404960

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000404960

ENSP00000406208

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000406208

ENSP00000412617

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000412617

ENSP00000414191

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000414191

ENSP00000417020

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000417020

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21109159&oldid=2022936559"