integrin subunit alpha 2b (Q21107760)

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mammalian protein found in Homo sapiens

platelet-specific antigen BAK
platelet glycoprotein IIb of IIb/IIIa complex
alphaIIb protein
ITGA2B
GPIIb
integrin alpha-IIb
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
platelet membrane glycoprotein IIb
GPalpha IIb
platelet fibrinogen receptor, alpha subunit
protein phosphatase 1, regulatory subunit 93
Platelet Membrane Glycoprotein IIb

Language	Label	Description	Also known as
English	integrin subunit alpha 2b	mammalian protein found in Homo sapiens	platelet-specific antigen BAK platelet glycoprotein IIb of IIb/IIIa complex alphaIIb protein ITGA2B GPIIb integrin alpha-IIb integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) platelet membrane glycoprotein IIb GPalpha IIb platelet fibrinogen receptor, alpha subunit protein phosphatase 1, regulatory subunit 93 Platelet Membrane Glycoprotein IIb

Statements

1 reference

13 November 2019

UniProt protein ID

Integrin domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08514

integrin alpha chain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08514

Integrin alpha, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08514

Integrin alpha beta-propellor, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha-2, protein family

1 reference

based on heuristic

inferred from protein domain or family

FG-GAP repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha chain, C-terminal cytoplasmic region, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

4 references

8 April 2019

Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

8 April 2019

NMR structure of the flavin domain from soluble methane monooxygenase reductase from Methylococcus capsulatus (Bath)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

8 April 2019

Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

8 April 2019

The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

fibrinogen binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

extracellular matrix binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

identical protein binding

determination method

3 references

8 April 2019

Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

8 April 2019

Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

8 April 2019

Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

integrin complex

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

integral component of plasma membrane

determination method

1 reference

17 October 2017

Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08514&geneProductId=UniProtKB:P08514

determination method

platelet alpha granule membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

external side of plasma membrane

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Exosomal-like vesicles are present in human blood plasma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

plasma membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

blood microparticle

determination method

1 reference

17 October 2017

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08514&geneProductId=UniProtKB:P08514

determination method

blood microparticle

determination method

1 reference

8 April 2019

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

biological process

extracellular matrix organization

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

cell-matrix adhesion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

positive regulation of leukocyte migration

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

platelet aggregation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

platelet degranulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

determination method

4 references

17 October 2017

A CD9, alphaIIbbeta3, integrin-associated protein, and GPIb/V/IX complex on the surface of human platelets is influenced by alphaIIbbeta3 conformational states

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08514&geneProductId=UniProtKB:P08514

determination method

17 October 2017

Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08514&geneProductId=UniProtKB:P08514

determination method

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08514&geneProductId=UniProtKB:P08514

determination method

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08514&geneProductId=UniProtKB:P08514

determination method

regulation of megakaryocyte differentiation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08514

determination method

physically interacts with

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1174

tirofiban hydrochloride hydrate

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3189072

Identifiers

MeSH descriptor ID

subject named as

Platelet Membrane Glycoprotein IIb

0 references

D12.776.543.750.705.408.100.950

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000262407

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000262407

ENSP00000467269

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000467269

ENSP00000498119

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000498119

0 references

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

24 May 2023

Sitelinks

Wikipedia(7 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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