Antioxidant 1 copper chaperone (Q21106530)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00244

Heavy metal-associated domain, HMA, protein family

1 reference

based on heuristic

inferred from protein domain or family

Heavy-metal-associated, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

copper ion transmembrane transporter activity

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00244&geneProductId=UniProtKB:O00244

metallochaperone activity

1 reference

8 April 2019

An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

3 references

8 April 2019

The copper-transporting capacity of ATP7A mutants associated with Menkes disease is ameliorated by COMMD1 as a result of improved protein expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

copper chaperone activity

IPI

1 reference

24 April 2018

Metallochaperone Atox1 transfers copper to the NH2-terminal domain of the Wilson's disease protein and regulates its catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00244&geneProductId=UniProtKB:O00244

copper-dependent protein binding

IDA

1 reference

8 April 2019

Characterization of the interaction between the Wilson and Menkes disease proteins and the cytoplasmic copper chaperone, HAH1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

copper chaperone activity

1 reference

8 April 2019

Metallochaperone Atox1 transfers copper to the NH2-terminal domain of the Wilson's disease protein and regulates its catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

3 references

8 April 2019

Metallochaperone Atox1 transfers copper to the NH2-terminal domain of the Wilson's disease protein and regulates its catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

3 references

8 April 2019

An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

copper ion transmembrane transport

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00244&geneProductId=UniProtKB:O00244

cellular copper ion homeostasis

3 references

8 April 2019

HAH1 is a copper-binding protein with distinct amino acid residues mediating copper homeostasis and antioxidant defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

response to oxidative stress

IBA

3 references

8 April 2019

HAH1 is a copper-binding protein with distinct amino acid residues mediating copper homeostasis and antioxidant defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

protein maturation by copper ion transfer

IBA

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00244&geneProductId=UniProtKB:O00244

negative regulation of apoptotic process

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00244

Heavy metal-associated domain, HMA

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00244

Heavy-metal-associated, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00244

Identifiers

MeSH descriptor ID

C474500

subject named as

ATOX1 protein, human

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

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1 reference

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1 reference

1 reference

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference