Nuclear factor, erythroid 2 (Q21101338)

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mammalian protein found in Homo sapiens

nuclear factor (erythroid-derived 2), 45kD
nuclear factor (erythroid-derived 2), 45kDa
nuclear factor, erythroid-derived 2 45 kDa subunit
leucine zipper protein NF-E2
p45 NF-E2
transcription factor NF-E2 45 kDa subunit
NFE2

Language	Label	Description	Also known as
English	Nuclear factor, erythroid 2	mammalian protein found in Homo sapiens	nuclear factor (erythroid-derived 2), 45kD nuclear factor (erythroid-derived 2), 45kDa nuclear factor, erythroid-derived 2 45 kDa subunit leucine zipper protein NF-E2 p45 NF-E2 transcription factor NF-E2 45 kDa subunit NFE2

Statements

1 reference

13 November 2019

UniProt protein ID

Transcription factor NF-E2, 45kDa subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16621

Transcription factor, Skn-1-like, DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16621

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Basic leucine zipper domain, Maf-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein N-terminus binding

determination method

1 reference

8 April 2019

NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

transcription coactivator activity

determination method

1 reference

8 April 2019

Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

transcription cis-regulatory region binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

DNA-binding transcription factor activity

determination method

4 references

8 April 2019

Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

sequence-specific DNA binding

determination method

1 reference

8 April 2019

Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

cis-regulatory region sequence-specific DNA binding

determination method

1 reference

8 April 2019

Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

determination method

3 references

27 March 2018

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16621&geneProductId=UniProtKB:Q16621

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16621&geneProductId=UniProtKB:Q16621

determination method

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16621&geneProductId=UniProtKB:Q16621

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

protein-DNA complex

determination method

1 reference

8 April 2019

A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

determination method

4 references

8 April 2019

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

biological process

determination method

1 reference

8 April 2019

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

blood coagulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

blood circulation

determination method

1 reference

8 April 2019

Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

multicellular organism development

determination method

1 reference

8 April 2019

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

27 March 2018

Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16621&geneProductId=UniProtKB:Q16621

determination method

nucleosome disassembly

determination method

1 reference

8 April 2019

Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

regulation of megakaryocyte differentiation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16621

determination method

Basic leucine zipper domain, Maf-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16621

Basic-leucine zipper domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16621

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000312436

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000312436

ENSP00000397185

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397185

ENSP00000439120

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000439120

ENSP00000447558

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000447558

ENSP00000446929

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000446929

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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