DNA polymerase theta (Q21101126)

Ribonuclease H-like superfamily

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

Ribonuclease H superfamily

1 reference

DNA-directed DNA polymerase, family A, palm domain, protein family

1 reference

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

Helicase, C-terminal domain, protein family

1 reference

DEAD/DEAH box helicase

1 reference

DNA-directed DNA polymerase, family A, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

nucleotidyltransferase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

single-stranded DNA helicase activity

1 reference

8 April 2019

POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

5'-deoxyribose-5-phosphate lyase activity

IDA

1 reference

8 April 2019

Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

DNA-directed DNA polymerase activity

7 references

8 April 2019

Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

Promiscuous DNA synthesis by human DNA polymerase θ

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

2 references

5'-3' exonuclease activity

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75417&geneProductId=UniProtKB:O75417

identical protein binding

IBA

1 reference

21 June 2018

Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75417&geneProductId=UniProtKB:O75417

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

cellular response to DNA damage stimulus

IBA

biological process

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

double-strand break repair via homologous recombination

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

protein homooligomerization

TAS

1 reference

8 April 2019

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

3 references

8 April 2019

Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

1 reference

8 April 2019

Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

IDA

DNA biosynthetic process

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

double-strand break repair

1 reference

8 April 2019

Promiscuous DNA synthesis by human DNA polymerase θ

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75417

nucleic acid phosphodiester bond hydrolysis

IDA

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75417&geneProductId=UniProtKB:O75417

DNA-directed DNA polymerase, family A, conserved site

has part(s)

1 reference

DEAD/DEAH box helicase domain

1 reference

Helicase superfamily 1/2, ATP-binding domain

1 reference

DNA-directed DNA polymerase, family A, palm domain

1 reference

Helicase, C-terminal

1 reference

D08.811.913.696.445.308.300.622

Identifiers

MeSH descriptor ID

D000097462

subject named as

DNA Polymerase theta

0 references

MeSH tree code

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016