menin (Q1920577)

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mammalian protein found in Homo sapiens
  • MEN1
  • uniprot:O00255
  • menin 1
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Language Label Description Also known as
English
menin
mammalian protein found in Homo sapiens
  • MEN1
  • uniprot:O00255
  • menin 1

Statements

molecular function
protein binding
determination method
IPI
14 references
retrieved
8 April 2019
stated in
The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin interacts directly with the homeobox-containing protein Pem
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin associates with FANCD2, a protein involved in repair of DNA damage
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin associates with FANCD2, a protein involved in repair of DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
Menin stimulates homology-directed DNA repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
retrieved
8 April 2019
stated in
HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
8 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IEA
retrieved
8 April 2019
stated in
Menin, the product of the MEN1 gene, is a nuclear protein
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IDA
retrieved
8 April 2019
stated in
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IDA
retrieved
8 April 2019
stated in
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain
GOA
curator
UniProt
UniProt protein ID
O00255
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IDA
retrieved
8 April 2019
stated in
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IDA
retrieved
8 April 2019
stated in
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255
determination method
IDA
biological process
Gene Atlas image
PBB GE MEN1 202645 s at fs.png
732 × 530; 12 KB
0 references

Identifiers

RefSeq protein ID
PDB structure ID
 
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