senescence-associated heterochromatin focus (Q14906999)

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A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.
  • GO:0035985
  • senescence-associated heterochromatin foci
  • SAHF
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English
senescence-associated heterochromatin focus
A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.
  • GO:0035985
  • senescence-associated heterochromatin foci
  • SAHF

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