lewprorelin (Q907160)

PubChem CID ^Saesneg

Leuprorelin (Saesneg)

19 Tachwedd 2016

SMILES

CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6

1 ffynhonnell

PubChem CID ^Saesneg

Leuprorelin (Saesneg)

19 Tachwedd 2016

isomeric SMILES ^Saesneg

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6

1 ffynhonnell

PubChem CID ^Saesneg

Leuprorelin (Saesneg)

19 Tachwedd 2016

defined daily dose ^Saesneg

1 milligram

dull gweini

parenteral route of administration ^Saesneg

1 ffynhonnell

https://www.whocc.no/atc_ddd_index/?code=L02AE02

0.134 milligram

dull gweini

parenteral route of administration ^Saesneg

1 ffynhonnell

https://www.whocc.no/atc_ddd_index/?code=L02AE02

cynhwysyn actif yn

Lupron Depot ^Saesneg

0 ffynonellau

World Health Organisation international non-proprietary name ^Saesneg

leuprorelin (Saesneg)

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

Leuprolide (Saesneg)

19 Ionawr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

carsinoma endometriaidd

1 ffynhonnell

NDF-RT ^Saesneg

NDF-RT

N0000147889

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

leiomyoma ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

NDF-RT

N0000147889

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

2 ffynonellau

NDF-RT ^Saesneg

13 Rhagfyr 2016

Drug Indications Extracted from FAERS ^Saesneg

2 Hydref 2018

precocious puberty ^Saesneg

1 ffynhonnell

Drug Indications Extracted from FAERS ^Saesneg

dyddiad neu amser cychwyn

2 Hydref 2018

endometriosis

25 Hydref 1995

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/EFY6W0M8TG

http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020011s040lbl.pdf

adweithia'n ffisegol gyda

Gonadotropin releasing hormone receptor ^Saesneg

rôl y pwnc

agonist ^Saesneg

1 ffynhonnell

dynodwr Llawlyfr Ffarmacoleg Ligand

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

1175

17 Awst 2016

LiverTox likelihood score ^Saesneg

LiverTox toxicity likelihood category E ^Saesneg

1 ffynhonnell

LiverTox ^Saesneg

8 Ebrill 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Leuprolide

last update ^Saesneg

22 Mawrth 2018

màs

1,208.645462 uned Dalton

1 ffynhonnell

PubChem CID ^Saesneg

Leuprorelin (Saesneg)

3 Hydref 2016

1 ffynhonnell

Leuprolide (Saesneg)

DrugBank ^Saesneg

Dynodwr Drugbank (Alberta)

dyddiad cyhoeddi

17 Tachwedd 2015

DB00007

rôl y pwnc

hormonal antineoplastic agent ^Saesneg

1 ffynhonnell

15 Mawrth 2018

female fertility agents ^Saesneg

1 ffynhonnell

15 Mawrth 2018

0 ffynonellau

Leuprorelin

0 ffynonellau

Identifiers

InChI

InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1

1 ffynhonnell

seiliwyd ar dybiaethau esboniadol

inferred from SMILES ^Saesneg

InChIKey ^Saesneg

2 ffynonellau

PubChem CID ^Saesneg

Leuprorelin (Saesneg)

19 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

53714-56-0

1 ffynhonnell

Global Substance Registration System ^Saesneg

UNII ^Saesneg

EFY6W0M8TG

leuprolide (Saesneg)

19 Tachwedd 2016

ChemSpider ID ^Saesneg

571356

1 ffynhonnell

ChemSpider

ChemSpider ID ^Saesneg

571356

Leuprorelin (Saesneg)

19 Tachwedd 2016

PubChem CID ^Saesneg

2 ffynonellau

PubChem CID ^Saesneg

Leuprorelin (Saesneg)

19 Tachwedd 2016

InChIKey

InChIKey ^Saesneg

Reaxys registry number ^Saesneg

741818

1 ffynhonnell

ChEBI

ChEBI ID ^Saesneg

6427

leuprolide (Saesneg)

3 Hydref 2016

ChEBI ID ^Saesneg

6427

mapping relation type ^Saesneg

exact match ^Saesneg

2 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

LEUPROLIDE (Saesneg)

19 Tachwedd 2016

InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1

International Chemical Identifier ^Saesneg

InChI

ChEMBL ID ^Saesneg

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

LEUPROLIDE (Saesneg)

seiliwyd ar dybiaethau esboniadol

19 Tachwedd 2016

SureChEMBL ID ^Saesneg

4585

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey

InChIKey ^Saesneg

UniChem compound ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

LEUPROLIDE (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID50872411

2 ffynonellau

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

InChIKey

InChIKey ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID00820063

0 ffynonellau

LiverTox ID ^Saesneg

Leuprolide

0 ffynonellau

NSC number ^Saesneg

377526

0 ffynonellau

EC number ^Saesneg

633-395-9

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.161.466

27 Rhagfyr 2018

1-[5-carbamimidamido-2-(2-{2-[2-(3-hydroxy-2-{2-[3-(1H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido}propanamido)-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido}-4-methylpentanamido)pentanoyl]-N-ethylpyrrolidine-2-carboxamide (Saesneg)

dyfyniad

CAS no.: 53714-56-0 (Saesneg)

ECHA Substance Infocard ID ^Saesneg

100.161.466

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.161.466

27 Rhagfyr 2018

1-[5-carbamimidamido-2-(2-{2-[2-(3-hydroxy-2-{2-[3-(1H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido}propanamido)-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido}-4-methylpentanamido)pentanoyl]-N-ethylpyrrolidine-2-carboxamide (Saesneg)

dyfyniad

CAS no.: 53714-56-0 (Saesneg)

Cod yr ATC

L02AE02

1 ffynhonnell

Dynodwr Drugbank (Alberta)

DrugBank ^Saesneg

DB00007