lincomycin (Q423428)

Gene Ontology release 2019-11-16 ^Saesneg

lincomycin catabolic process ^Saesneg

rôl y pwnc

reactant ^Saesneg

1 ffynhonnell

Gene Ontology release 2019-11-16 ^Saesneg

lincomycin biosynthetic process ^Saesneg

rôl y pwnc

product ^Saesneg

1 ffynhonnell

Gene Ontology release 2019-11-16 ^Saesneg

1 ffynhonnell

Lincomycin (Saesneg)

DrugBank ^Saesneg

dyddiad cyhoeddi

17 Tachwedd 2015

adeiledd gemegol

Lincomycin.png
610 × 456; 10 KB

0 ffynonellau

image of molecular model or crystal lattice model ^Saesneg

Lincomycin molecule ball.png
2,000 × 1,382; 560 KB

yn portreadu

ball-and-stick model ^Saesneg

0 ffynonellau

Lincomycin molecule spacefill.png
2,000 × 1,456; 612 KB

yn portreadu

space-filling model ^Saesneg

0 ffynonellau

màs

406.214 uned Dalton

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

lincomycin (Saesneg)

(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)-2-oxanyl]propyl]-1-methyl-4-propyl-2-pyrrolidinecarboxamide ^Saesneg

19 Hydref 2016

stereoisomer of ^Saesneg

2 ffynonellau

seiliwyd ar dybiaethau esboniadol

inferred from InChIKey ^Saesneg

seiliwyd ar dybiaethau esboniadol

inferred from InChI ^Saesneg

fformwla gemegol

C₁₈H₃₄N₂O₆S

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

isomeric SMILES ^Saesneg

CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O

0 ffynonellau

cynhwysyn actif yn

Lincocin ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

287531

14 Chwefror 2018

Lincobac ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

1540026

14 Chwefror 2018

Lincomed ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

656855

14 Chwefror 2018

LINCOCINE 500 mg, capsule ^Saesneg

1 ffynhonnell

BDPM ^Saesneg

26 Hydref 2020

http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=67544048

World Health Organisation international non-proprietary name ^Saesneg

lincomycin (Saesneg)

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lincomycin (Saesneg)

19 Hydref 2016

found in taxon ^Saesneg

Streptomyces lincolnensis ^Saesneg

23 ffynonellau

Sequence analysis and heterologous expression of the lincomycin biosynthetic cluster of the type strain Streptomyces lincolnensis ATCC 25466. ^Saesneg

Biosynthesis of the lincomycins. 2. Studies using stable isotopes on the biosynthesis of methylthiolincosaminide moiety of lincomycin A ^Saesneg

Isolation and identification of 3-propylidene-delta 1-pyrroline-5-carboxylic acid, a biosynthetic precursor of lincomycin ^Saesneg

Putative lmbI and lmbH genes form a single lmbIH ORF in Streptomyces lincolnensis type strain ATCC 25466. ^Saesneg

LmbJ and LmbIH protein levels correlate with lincomycin production in Streptomyces lincolnensis ^Saesneg

Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production ^Saesneg

An efficient intergeneric conjugation of DNA from Escherichia coli to mycelia of the lincomycin-producer Streptomyces lincolnensis ^Saesneg

Effects of flow field on the metabolic characteristics of Streptomyces lincolnensis in the industrial fermentation of lincomycin ^Saesneg

Defining a kinetic mechanism for l-DOPA 2,3 dioxygenase, a single-domain type I extradiol dioxygenase from Streptomyces lincolnensis. ^Saesneg

Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis ^Saesneg

The novel transcriptional regulator LmbU promotes lincomycin biosynthesis through regulating expression of its target genes in Streptomyces lincolnensis ^Saesneg

Global regulator BldA regulates morphological differentiation and lincomycin production in Streptomyces lincolnensis ^Saesneg

Enhanced lincomycin production by co-overexpression of metK1 and metK2 in Streptomyces lincolnensis. ^Saesneg

Negative Involvement of the TetR-type regulator SLCG_2919 in the regulation of lincomycin biosynthesis in ^Saesneg

AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensis ^Saesneg

A family of r-determinants in Streptomyces spp. that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibiotics. ^Saesneg

Monophenol monooxygenase and lincomysin biosynthesis in Streptomyces lincolnensis ^Saesneg

Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11 ^Saesneg

The genes lmbB1 and lmbB2 of Streptomyces lincolnensis encode enzymes involved in the conversion of L-tyrosine to propylproline during the biosynthesis of the antibiotic lincomycin A ^Saesneg

Biosynthesis of the lincomycins. 1. Studies using stable isotopes on the biosynthesis of the propyl- and ethyl-L-hygric acid moieties of lincomycins A and B ^Saesneg

Developmental regulator BldD directly regulates lincomycin biosynthesis in Streptomyces lincolnensis ^Saesneg

Effects of phosphate, glucose, and ammonium on cell growth and lincomycin production by Streptomyces lincolnensis in chemically defined media ^Saesneg

Erratum for Hou et al., "The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis". ^Saesneg

Streptomyces albidoflavus ^Saesneg

1 ffynhonnell

Identification of a Novel Lincomycin Resistance Mutation Associated with Activation of Antibiotic Production in Streptomyces coelicolor A3(2). ^Saesneg

Streptomyces coelicolor ^Saesneg

1 ffynhonnell

Identification of a Novel Lincomycin Resistance Mutation Associated with Activation of Antibiotic Production in Streptomyces coelicolor A3(2). ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

dyddiad neu amser cychwyn

13 Rhagfyr 2016

clefyd staffylococol

29 Rhagfyr 1964

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/BOD072YW0F

http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/050317s179s180lbl.pdf

haint niwmococol

dyddiad neu amser cychwyn

29 Rhagfyr 1964

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/BOD072YW0F

http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/050317s179s180lbl.pdf

legal status (medicine) ^Saesneg

boxed warning ^Saesneg

1 ffynhonnell

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

categori beichiogrwydd Unol Daleithiau America C

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (Saesneg)

categori beichiogrwydd

1 ffynhonnell

1 ffynhonnell

15 Mawrth 2018

protein synthesis inhibitor ^Saesneg

1 ffynhonnell

15 Mawrth 2018

‎WHO Aware Classification ^Saesneg

watch ^Saesneg

1 ffynhonnell

InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1

2023 ‎AWaRe classification‎ ^Saesneg

0 ffynonellau

0 ffynonellau

Lincomycin

0 ffynonellau

Identifiers

InChI

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

lincomycin (Saesneg)

OJMMVQQUTAEWLP-KIDUDLJLSA-N

20 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

154-21-2

2 ffynonellau

UNII ^Saesneg

lincomycin (Saesneg)

OJMMVQQUTAEWLP-KIDUDLJLSA-N

20 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

9 Ebrill 2021

https://commonchemistry.cas.org/detail?cas_rn=154-21-2

ChemSpider ID ^Saesneg

2272112

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

2272112

lincomycin (Saesneg)

20 Tachwedd 2016

PubChem CID ^Saesneg

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

Reaxys registry number ^Saesneg

707677

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lincomycin (Saesneg)

19 Hydref 2016

ChEBI ID ^Saesneg

mapping relation type ^Saesneg

exact match ^Saesneg

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL1447

LINCOMYCIN (Saesneg)

20 Tachwedd 2016

ChEMBL ID ^Saesneg

CHEMBL1447

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL1447

LINCOMYCIN (Saesneg)

20 Tachwedd 2016

UniChem compound ID ^Saesneg

264690

1 ffynhonnell

MSBNK-Athens_Univ-AU118001

UniChem ^Saesneg

MassBank accession ID ^Saesneg

0 ffynonellau

0 ffynonellau

0 ffynonellau

0 ffynonellau

0 ffynonellau

0 ffynonellau

0 ffynonellau

0 ffynonellau

0 ffynonellau

SPLASH ^Saesneg

splash10-004i-0900000000-70466cfb7e0692d073a0

0 ffynonellau

splash10-004i-0900000000-b712dc39bbf605193fb4

0 ffynonellau

splash10-0a4i-0109000000-cdbfa33f16a571dd85ee

0 ffynonellau

splash10-0a4i-0209000000-8ec5c595eb6720c93c13

0 ffynonellau

splash10-000j-0900000000-1f46f29c3d5dbc6c25f6

0 ffynonellau

splash10-0002-0901000000-3fc103447a71fd95cedd

0 ffynonellau

splash10-016r-0895000000-4b0507fffd39d9fc075f

0 ffynonellau

splash10-00mk-0952000000-ca2f735ea2244e1cb32e

0 ffynonellau

dynodwr HSDB

3109

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

LINCOMYCIN (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID3023215

1 ffynhonnell

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID003215

0 ffynonellau

EC number ^Saesneg

205-824-6

1 ffynhonnell

UNII ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

ECHA Substance Infocard ID ^Saesneg

100.005.296

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

27 Rhagfyr 2018

Lincomycin (Saesneg)

CAS no.: 154-21-2 (Saesneg)

AICS Chemical ID (BEING DELETED) ^Saesneg

0 ffynonellau

1 ffynhonnell

DrugBank ^Saesneg

dynodwr Llawlyfr Ffarmacoleg Ligand

Lincomycin (Saesneg)

dyddiad cyhoeddi

17 Tachwedd 2015

10941

1 ffynhonnell

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

5 Chwefror 2021

Lincomycin

0 ffynonellau

Cod MeSH

D03.383.773.532.500

0 ffynonellau

D09.408.471.500

0 ffynonellau

RxNorm ID ^Saesneg

6398

1 ffynhonnell

UNII ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

1 ffynhonnell

DrugBank ^Saesneg

Lincomycin (Saesneg)

17 Tachwedd 2015

0 ffynonellau

UNII ^Saesneg

1 ffynhonnell

UNII ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

1 ffynhonnell

UNII ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

Probes And Drugs ID ^Saesneg

PD013336

0 ffynonellau

DrugCentral ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lincomycin (Saesneg)

19 Hydref 2016

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lincomycin (Saesneg)

19 Hydref 2016

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

lincomycin (Saesneg)

19 Hydref 2016

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

dynodwr Encyclopædia Britannica Online

lincomycin (Saesneg)

19 Hydref 2016

0 ffynonellau

DeCS ID ^Saesneg

23297

0 ffynonellau

science/lincomycin

enwyd fel

lincomycin

rheswm dros anghymeradwyo

withdrawn identifier value ^Saesneg

0 ffynonellau

dynodwr Freebase

/m/0b707f

1 ffynhonnell

dynodwr Gran Enciclopèdia Catalana

Freebase Data Dumps ^Saesneg

dyddiad cyhoeddi

28 Hydref 2013

Gran Enciclopèdia Catalana ID ^Saesneg

lincomicina-0

0 ffynonellau

0119423

0 ffynonellau

dynodwr Microsoft Academic

2778985905

0 ffynonellau

2910385908

0 ffynonellau

OpenAlex ID ^Saesneg

1 ffynhonnell

OpenAlex ^Saesneg

26 Ionawr 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID ^Saesneg

4WH5

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4WH5

4WH5 (Saesneg)

19 Hydref 2016

Römpp online ID ^Saesneg

1 ffynhonnell

UMLS CUI ^Saesneg

1 ffynhonnell

UNII ^Saesneg

lincomycin (Saesneg)

20 Tachwedd 2016

WikiProjectMed ID ^Saesneg

Lincomycin

0 ffynonellau

WordNet 3.1 Synset ID ^Saesneg

03675948-n

1 ffynhonnell