irinotecan (Q412197)

irinotecan (Saesneg)

19 Tachwedd 2016

CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

1 ffynhonnell

irinotecan (Saesneg)

19 Tachwedd 2016

isomeric SMILES ^Saesneg

CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

1 ffynhonnell

irinotecan (Saesneg)

19 Tachwedd 2016

Camptosar ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm CUI ^Saesneg

203652

14 Chwefror 2018

World Health Organisation international non-proprietary name ^Saesneg

irinotecan (Saesneg)

1 ffynhonnell

ChEBI

ChEBI ID ^Saesneg

80630

irinotecan (Saesneg)

Taiwanofungus camphoratus

19 Hydref 2016

found in taxon ^Saesneg

1 ffynhonnell

Antcamphorols A-K, Cytotoxic and ROS Scavenging Triterpenoids from Antrodia camphorata ^Saesneg

Gwylys

1 ffynhonnell

Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. ^Saesneg

1 ffynhonnell

13 Rhagfyr 2016

1 ffynhonnell

carsinoma di-gell-bychain

13 Rhagfyr 2016

1 ffynhonnell

13 Rhagfyr 2016

1 ffynhonnell

13 Rhagfyr 2016

neoplasm diniwed colonig

1 ffynhonnell

13 Rhagfyr 2016

1 ffynhonnell

13 Rhagfyr 2016

2 ffynonellau

13 Rhagfyr 2016

2 Hydref 2018

1 ffynhonnell

13 Rhagfyr 2016

colon cancer ^Saesneg

1 ffynhonnell

2 Hydref 2018

germ cell cancer ^Saesneg

1 ffynhonnell

2 Hydref 2018

alveolar rhabdomyosarcoma ^Saesneg

1 ffynhonnell

2 Hydref 2018

colon adenocarcinoma ^Saesneg

1 ffynhonnell

2 Hydref 2018

pancreatic adenocarcinoma ^Saesneg

1 ffynhonnell

2 Hydref 2018

canser ar yr ymennydd

1 ffynhonnell

2 Hydref 2018

rectum adenocarcinoma ^Saesneg

1 ffynhonnell

2 Hydref 2018

neuroblastoma, susceptibility to ^Saesneg

1 ffynhonnell

dyddiad neu amser cychwyn

2 Hydref 2018

canser colorectaidd

14 Mehefin 1996

cadarnhawyd gan

United States Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

https://drugs.ncats.io/drug/7673326042

2 Tachwedd 2018

cyfeirnod URL

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf

significant drug interaction ^Saesneg

amiodaron

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

amprenafir

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

aprepitant ^Saesneg

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

atasanafir

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

cimetidin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

clarithromycin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

darunavir ^Saesneg

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

diltiasem

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

erythromycin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

fflwconasol

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

fosamprenavir ^Saesneg

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

indinafir

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

itraconasol

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

cetoconasol

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

lopinafir

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

neffasodon

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

nelffinafir

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

ritonafir

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

sacwinafir

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

telithromycin ^Saesneg

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

tipranavir ^Saesneg

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

ferapamil

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

foriconasol

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

idelalisib ^Saesneg

side effect ^Saesneg

bone marrow failure ^Saesneg

1 ffynhonnell

manylrwydd y gosodiad

hypothetically ^Saesneg

categori beichiogrwydd Awstralia D

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

categori beichiogrwydd

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

categori beichiogrwydd Unol Daleithiau America D

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

màs

586.279 uned Dalton

1 ffynhonnell

InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3/t33-/m0/s1

irinotecan (Saesneg)

19 Hydref 2016

DNA polymerase inhibitors ^Saesneg

1 ffynhonnell

5 Mawrth 2018

topoisomerase inhibitor ^Saesneg

1 ffynhonnell

5 Mawrth 2018

phytogenic antineoplastic agents ^Saesneg

1 ffynhonnell

15 Mawrth 2018

radiosensitizer ^Saesneg

1 ffynhonnell

15 Mawrth 2018

topoisomerase I inhibitor ^Saesneg

1 ffynhonnell

15 Mawrth 2018

0 ffynonellau

Irinotecan

0 ffynonellau

Identifiers

InChI

1 ffynhonnell

irinotecan (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

irinotecan (Saesneg)

19 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

97682-44-5

2 ffynonellau

Global Substance Registration System ^Saesneg

UNII ^Saesneg

7673326042

irinotecan (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

https://commonchemistry.cas.org/detail?cas_rn=97682-44-5

10 Ebrill 2021

cyfeirnod URL

ChemSpider ID ^Saesneg

54825

1 ffynhonnell

ChemSpider

ChemSpider ID ^Saesneg

54825

Irinotecan (Saesneg)

19 Tachwedd 2016

2 ffynonellau

irinotecan (Saesneg)

19 Tachwedd 2016

InChIKey

InChIKey ^Saesneg

Reaxys registry number ^Saesneg

4839096

1 ffynhonnell

ChEBI

ChEBI ID ^Saesneg

80630

irinotecan (Saesneg)

19 Hydref 2016

ChEBI ID ^Saesneg

80630

mapping relation type ^Saesneg

exact match ^Saesneg

2 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL481

IRINOTECAN (Saesneg)

19 Tachwedd 2016

International Chemical Identifier

InChI

InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3/t33-/m0/s1

ChEMBL ID ^Saesneg

CHEMBL481

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL481

IRINOTECAN (Saesneg)

seiliwyd ar dybiaethau esboniadol

19 Tachwedd 2016

SureChEMBL ID ^Saesneg

4034

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey

InChIKey ^Saesneg

UniChem compound ID ^Saesneg

1 ffynhonnell

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

IRINOTECAN (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID1041051

2 ffynonellau

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

InChIKey

InChIKey ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID9021051

0 ffynonellau

LiverTox ID ^Saesneg

IrinotecanTopotecan

0 ffynonellau

NSC number ^Saesneg

728073

0 ffynonellau

EC number ^Saesneg

691-567-9

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.219.260

27 Rhagfyr 2018

(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate (Saesneg)

dyfyniad

CAS no.: 97682-44-5 (Saesneg)

ECHA Substance Infocard ID ^Saesneg

100.219.260

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.219.260

27 Rhagfyr 2018

(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate (Saesneg)

dyfyniad

CAS no.: 97682-44-5 (Saesneg)

Cod yr ATC

L01XX19

1 ffynhonnell

Dynodwr Drugbank (Alberta)

DrugBank ^Saesneg

DB00762