TNF receptor superfamily member 11a (Q906651)

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mammalian protein found in Homo sapiens

osteoclast differentiation factor receptor
ODFR
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
loss of heterozygosity, 18, chromosomal region 1
tumor necrosis factor receptor superfamily member 11A
receptor activator of NF-KB
receptor activator of nuclear factor-kappa B
TNFRSF11A
Paget disease of bone 2
RANK

Language	Label	Description	Also known as
English	TNF receptor superfamily member 11a	mammalian protein found in Homo sapiens	osteoclast differentiation factor receptor ODFR tumor necrosis factor receptor superfamily, member 11a, NFKB activator loss of heterozygosity, 18, chromosomal region 1 tumor necrosis factor receptor superfamily member 11A receptor activator of NF-KB receptor activator of nuclear factor-kappa B TNFRSF11A Paget disease of bone 2 RANK

Statements

1 reference

13 November 2019

UniProt protein ID

Tumour necrosis factor receptor 11A

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y6Q6

Tumor necrosis factor receptor 11A, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

TNFR/NGFR cysteine-rich region, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

metal ion binding

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

protein binding

determination method

tumor necrosis factor-activated receptor activity

determination method

3 references

transmembrane signaling receptor activity

determination method

1 reference

1 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

cytokine binding

determination method

1 reference

1 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

signaling receptor activity

determination method

1 reference

1 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

integral component of membrane

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

integral component of plasma membrane

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6Q6&geneProductId=UniProtKB:Q9Y6Q6

determination method

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

external side of plasma membrane

determination method

1 reference

1 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

determination method

1 reference

1 January 2018

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

plasma membrane

determination method

3 references

biological process

regulation of apoptotic process

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6Q6&geneProductId=UniProtKB:Q9Y6Q6

determination method

response to cytokine

determination method

1 reference

1 January 2018

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

adaptive immune response

determination method

1 reference

1 January 2018

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

monocyte chemotaxis

determination method

1 reference

1 January 2018

Expression and function of RANK in human monocyte chemotaxis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

positive regulation of JUN kinase activity

determination method

1 reference

1 January 2018

TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

osteoclast differentiation

determination method

1 reference

1 January 2018

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

cell-cell signaling

determination method

1 reference

1 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

positive regulation of DNA-binding transcription factor activity

determination method

3 references

1 January 2018

Central control of fever and female body temperature by RANKL/RANK

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

1 January 2018

TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

tumor necrosis factor-mediated signaling pathway

determination method

mammary gland alveolus development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

multicellular organism development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

response to lipopolysaccharide

determination method

3 references

positive regulation of NF-kappaB transcription factor activity

determination method

positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling

determination method

1 reference

1 January 2018

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

positive regulation of cell population proliferation

determination method

1 reference

1 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

apoptotic signaling pathway

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6Q6&geneProductId=UniProtKB:Q9Y6Q6

determination method

response to radiation

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

TNFSF11-mediated signaling pathway

determination method

1 reference

1 January 2018

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

inflammatory response

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6Q6&geneProductId=UniProtKB:Q9Y6Q6

determination method

lymph node development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

signal transduction

determination method

1 reference

1 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

positive regulation of bone resorption

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

multinuclear osteoclast differentiation

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6Q6

determination method

Gene Atlas image

PBB GE TNFRSF11A 207037 at fs.png
732 × 530; 12 KB

0 references

TNFR/NGFR cysteine-rich region

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y6Q6

Tumor necrosis factor receptor 11A, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y6Q6

Identifiers

MeSH descriptor ID

subject named as

Receptor Activator of Nuclear Factor-kappa B

0 references

D12.776.543.750.705.852.760.345

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000482466

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482466

ENSP00000269485

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000269485

ENSP00000465500

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000465500

ENSP00000479567

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000479567

ENSP00000492422

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492422

1 reference

Freebase Data Dumps

publication date

28 October 2013

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(8 entries)

azwiki RANK
dewiki RANK
enwiki RANK
eswiki RANK
glwiki RANK
itwiki RANK
ttwiki TNFRSF11A
ukwiki TNFRSF11A

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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