Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire (Q77328529)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10204492%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire (English)

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4 December 2019

1

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4 December 2019

author name string

I Stefanová

2

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4 December 2019

K Yasutomo

3

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4 December 2019

N Dautigny

4

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4 December 2019

R N Germain

5

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4 December 2019

publication date

1 March 1999

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4 December 2019

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4 December 2019

volume

10

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4 December 2019

issue

3

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4 December 2019

page(s)

367-376

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T-cell-receptor affinity and thymocyte positive selection

4 December 2019

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Positive and negative selection invoke distinct signaling pathways.

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Peptides in positive and negative selection: a delicate balance

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CD28-B7 interactions function to co-stimulate clonal deletion of double-positive thymocytes

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Another view of the selective model of thymocyte selection

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H-2 antigens of the thymus determinelymphocyte specificity

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T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

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CD4 Augments the Response of a T Cell to Agonist but Not to Antagonist Ligands

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T cell receptor antagonist peptides induce positive selection

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Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

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Specificity and flexibility in thymic selection

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T cell tolerance by clonal elimination in the thymus

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

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Fidelity of T Cell Activation Through Multistep T Cell Receptor ζ Phosphorylation

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High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

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Peripheral T Cell Survival Requires Continual Ligation of the T Cell Receptor to Major Histocompatibility Complex–Encoded Molecules

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Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes

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7 January 2021

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

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7 January 2021

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

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7 January 2021

Positive selection of CD4+ thymocytes controlled by MHC class II gene products

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7 January 2021

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7 January 2021

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Targeted Complementation of MHC Class II Deficiency by Intrathymic Delivery of Recombinant Adenoviruses

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7 January 2021

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7 January 2021

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7 January 2021

Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes

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7 January 2021

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

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7 January 2021

CD69 expression during selection and maturation of CD4+8+ thymocytes

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7 January 2021

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

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7 January 2021

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

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7 January 2021

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

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7 January 2021

Intracellular signals that mediate thymic negative selection

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7 January 2021

Endogenous altered peptide ligands can affect peripheral T cell responses

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7 January 2021

The thymus selects the useful, neglects the useless and destroys the harmful

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7 January 2021

Activating and Inhibitory Mutations in Adjacent Tyrosines in the Kinase Domain of ZAP-70

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7 January 2021

A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development

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7 January 2021

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

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7 January 2021

10.1016/S1074-7613(00)80036-9

Identifiers

DOI

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4 December 2019

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