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transforming growth factor beta receptor 1 (Q7670160)

From Wikidata
mammalian protein found in Homo sapiens
  • TGFBR1
  • TGF-beta receptor type-1
  • activin A receptor type II-like protein kinase of 53kD
  • ALK-5
  • serine/threonine-protein kinase receptor R4
  • TbetaR-I
  • transforming growth factor beta receptor I
  • SKR4
  • TGF-beta type I receptor
  • activin receptor-like kinase 5
  • mutant transforming growth factor beta receptor I
  • activin A receptor type II-like kinase, 53kDa
  • ALK5
  • TGF-beta receptor type I
  • transforming growth factor-beta receptor type I
  • Receptor, Transforming Growth Factor-beta Type I
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    English
    transforming growth factor beta receptor 1
    mammalian protein found in Homo sapiens
    • TGFBR1
    • TGF-beta receptor type-1
    • activin A receptor type II-like protein kinase of 53kD
    • ALK-5
    • serine/threonine-protein kinase receptor R4
    • TbetaR-I
    • transforming growth factor beta receptor I
    • SKR4
    • TGF-beta type I receptor
    • activin receptor-like kinase 5
    • mutant transforming growth factor beta receptor I
    • activin A receptor type II-like kinase, 53kDa
    • ALK5
    • TGF-beta receptor type I
    • transforming growth factor-beta receptor type I
    • Receptor, Transforming Growth Factor-beta Type I

    Statements

    molecular function
    transforming growth factor beta-activated receptor activity
    determination method or standard
    IC
    IDA
    IEA
    IMP
    6 references
    retrieved
    24 April 2018
    stated in
    Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    24 April 2018
    stated in
    TGF beta signals through a heteromeric protein kinase receptor complex
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    24 April 2018
    stated in
    SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IC
    protein binding
    determination method or standard
    IPI
    22 references
    retrieved
    8 April 2019
    stated in
    Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization
    GOA
    curator
    UniProt
    UniProt protein ID
    P36897
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Potentiation of Smad-mediated transcriptional activation by the RNA-binding protein RBPMS
    GOA
    curator
    UniProt
    UniProt protein ID
    P36897
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
    GOA
    curator
    UniProt
    UniProt protein ID
    P36897
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain
    GOA
    curator
    UniProt
    UniProt protein ID
    P36897
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma
    GOA
    curator
    UniProt
    UniProt protein ID
    P36897
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone
    GOA
    curator
    UniProt
    UniProt protein ID
    P36897
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
    GOA
    curator
    UniProt
    UniProt protein ID
    P36897
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Activation of signalling by the activin receptor complex
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor
    GOA
    curator
    AgBase
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    SMAD binding
    determination method or standard
    IDA
    IEA
    IPI
    5 references
    retrieved
    24 April 2018
    stated in
    TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    24 April 2018
    stated in
    MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    24 April 2018
    stated in
    SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    transforming growth factor beta binding
    determination method or standard
    IDA
    ISS
    IEA
    IMP
    IPI
    6 references
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    AgBase
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    ISS
    retrieved
    24 April 2018
    stated in
    Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    24 April 2018
    stated in
    TGF beta signals through a heteromeric protein kinase receptor complex
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    24 April 2018
    stated in
    SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    transforming growth factor beta-activated receptor activity
    determination method or standard
    IBA
    IC
    IDA
    IEA
    IMP
    7 references
    retrieved
    8 April 2019
    stated in
    Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    TGF beta signals through a heteromeric protein kinase receptor complex
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IC
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IBA
    SMAD binding
    determination method or standard
    IBA
    IDA
    IEA
    IPI
    6 references
    retrieved
    8 April 2019
    stated in
    TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IBA
    transforming growth factor beta binding
    determination method or standard
    IDA
    IEA
    IMP
    IPI
    5 references
    retrieved
    8 April 2019
    stated in
    Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    TGF beta signals through a heteromeric protein kinase receptor complex
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    cell component
    biological process
    transforming growth factor beta receptor signaling pathway
    determination method or standard
    IC
    ISS
    IEA
    IDA
    IMP
    TAS
    8 references
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    TAS
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    ISS
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    AgBase
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    ISS
    retrieved
    24 April 2018
    stated in
    TGF beta signals through a heteromeric protein kinase receptor complex
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    24 April 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    24 April 2018
    stated in
    Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    24 April 2018
    stated in
    Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P36897&geneProductId=UniProtKB:P36897
    determination method or standard
    IC
    transforming growth factor beta receptor signaling pathway
    determination method or standard
    IBA
    IC
    IDA
    IEA
    IMP
    ISS
    TAS
    8 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    TGF beta signals through a heteromeric protein kinase receptor complex
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IC
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36897
    determination method or standard
    IBA

    Identifiers

    MeSH descriptor ID
    D000077293
    subject named as
    Receptor, Transforming Growth Factor-beta Type I
    0 references
    PDB structure ID
     
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