TAL bHLH transcription factor 1, erythroid differentiation factor (Q7669284)

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

protein dimerization activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

1 reference

8 April 2019

DNA-binding transcription factor activity

1 reference

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

histone deacetylase binding

1 reference

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

transcription cis-regulatory region binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

protein binding

7 references

8 April 2019

Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

SCL binds the human homologue of DRG in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

protein heterodimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

enzyme binding

1 reference

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

4 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

histone deacetylase complex

cell component

1 reference

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

Lsd1/2 complex

1 reference

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17542&geneProductId=UniProtKB:P17542

4 references

21 June 2018

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17542&geneProductId=UniProtKB:P17542

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17542&geneProductId=UniProtKB:P17542

21 June 2018

21 June 2018

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17542&geneProductId=UniProtKB:P17542

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

megakaryocyte development

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

myeloid cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

1 reference

8 April 2019

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17542&geneProductId=UniProtKB:P17542

1 reference

21 June 2018

regulation of mast cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

spinal cord association neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

positive regulation of protein-containing complex assembly

1 reference

8 April 2019

NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

locomotory behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

positive regulation of erythrocyte differentiation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

regulation of stem cell population maintenance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

platelet formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

positive regulation of mitotic cell cycle

1 reference

8 April 2019

NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17542&geneProductId=UniProtKB:P17542

1 reference

21 June 2018

generation of neurons

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

basophil differentiation

IEP

1 reference

8 April 2019

Expression of tal-1 and GATA-binding proteins during human hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

positive regulation of transcription, DNA-templated

IEP

1 reference

8 April 2019

Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

1 reference

8 April 2019

regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

hematopoietic stem cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

astrocyte fate commitment

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

angiogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

erythrocyte differentiation

The SCL gene product: a positive regulator of erythroid differentiation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Expression of tal-1 and GATA-binding proteins during human hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

definitive hemopoiesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

regulation of myeloid cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

positive regulation of cell division

1 reference

8 April 2019

NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

hemangioblast cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

erythrocyte maturation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

regulation of hematopoietic stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

1 reference

8 April 2019

transcription by RNA polymerase II

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

negative regulation of erythrocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

positive regulation of protein tyrosine kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

positive regulation of signaling receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

regulation of transcription by RNA polymerase II

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17542

basic helix-loop-helix transcription factor

Gene Atlas image

PBB GE TAL1 206283 s at fs.png
732 × 530; 11 KB

0 references

Identifiers

MeSH descriptor ID

D000073942

subject named as

T-Cell Acute Lymphocytic Leukemia Protein 1

0 references

MeSH tree code

D12.776.260.103.829

broader concept

0 references

D12.776.624.664.700.960

broader concept

proto-oncogene protein

0 references

D12.776.930.125.829

broader concept

basic helix-loop-helix transcription factor

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

19 March 2016

language of work or name

1 reference

19 March 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023