An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysis (Q73661495)

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5 November 2019

title

An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysis (English)

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5 November 2019

author name string

S. Nesbitt

1

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14 November 2024

L. A. Hegg

2

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14 November 2024

M. J. Fedor

3

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publication date

1 August 1997

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August 1997

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National Center for Biotechnology Information

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14 November 2024

language of work or name

English

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National Center for Biotechnology Information

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https://doi.org/10.1016/s1074-5521(97)90247-7

14 November 2024

work available at URL

online access status

open access

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https://api.elsevier.com/content/article/PII:S1074552197902477?httpAccept=text/xml

14 November 2024

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14 November 2024

published in

Chemistry and Biology

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volume

4

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issue

8

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page(s)

619-630

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Self-cleaving catalytic RNA.

5 November 2019

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Catalytically active geometry in the reversible circularization of ‘mini-monomer’ RNAs derived from the complementary strand of tobacco ringspot virus satellite RNA

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Kinetics and thermodynamics of intermolecular catalysis by hairpin ribozymes

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Two histidine residues are essential for ribonuclease T1 activity as is the case for ribonuclease A

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Role of divalent metal ions in the hammerhead RNA cleavage reaction

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Metal ion catalysis in the Tetrahymena ribozyme reaction

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Stability constants of magnesium and cadmium complexes of adenine nucleotides and thionucleotides and rate constants for formation and dissociation of magnesium-ATP and magnesium-ADP

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Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding

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Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes

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Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism

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Binding and cleavage of nucleic acids by the "hairpin" ribozyme

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RNA mediated formation of a phosphorothioate diester bond.

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Uridine 2',3'-O,O-cyclophosphorothioate as substrate for pancreatic ribonuclease (I)

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A kinetic and thermodynamic framework for the hammerhead ribozyme reaction

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Comparison of pH dependencies of the Tetrahymena ribozyme reactions with RNA 2'-substituted and phosphorothioate substrates reveals a rate-limiting conformational step

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Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration

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A general two-metal-ion mechanism for catalytic RNA

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14 November 2024

Identifiers

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5 November 2019

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