MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice (Q73086909)

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1 November 2019

title

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice (English)

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1 November 2019

5

Irving L Weissman

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1 November 2019

3

Emmanuelle Passegué

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1 November 2019

author name string

Chi Wai So

1

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1 November 2019

Holger Karsunky

2

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1 November 2019

Antonio Cozzio

4

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1 November 2019

Michael L Cleary

6

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1 November 2019

publication date

1 February 2003

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1 November 2019

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1 November 2019

volume

3

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1 November 2019

issue

2

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1 November 2019

page(s)

161-171

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

1 November 2019

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An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

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The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

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A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

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The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

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The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

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Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines

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Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL

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The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis

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Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations

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Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

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Bipotential B-macrophage progenitors are present in adult bone marrow

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The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype

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Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region

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7 January 2021

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Development of CD8 -Positive Dendritic Cells from a Common Myeloid Progenitor

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Identifiers

DOI

1 reference

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1 November 2019

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