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Receptor activity modifying protein 1 (Q7275752)

From Wikidata

mammalian protein found in Homo sapiens

receptor (calcitonin) activity modifying protein 1
Calcitonin-receptor-like receptor activity-modifying protein 1
receptor activity-modifying protein 1
RAMP1
CRLR activity-modifying protein 1
calcitonin receptor-like receptor activity modifying protein 1
receptor (G protein-coupled) activity modifying protein 1

Language	Label	Description	Also known as
default for all languages	No label defined
English	Receptor activity modifying protein 1	mammalian protein found in Homo sapiens	receptor (calcitonin) activity modifying protein 1 Calcitonin-receptor-like receptor activity-modifying protein 1 receptor activity-modifying protein 1 RAMP1 CRLR activity-modifying protein 1 calcitonin receptor-like receptor activity modifying protein 1 receptor (G protein-coupled) activity modifying protein 1

Statements

1 reference

13 November 2019

UniProt protein ID

Receptor activity modifying protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60894

RAMP domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60894

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

coreceptor activity

determination method or standard

1 reference

3 January 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

calcitonin receptor activity

determination method or standard

1 reference

3 January 2017

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

calcitonin receptor binding

determination method or standard

1 reference

3 January 2017

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

protein binding

determination method or standard

5 references

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Involvement of vascular endothelial growth factor signaling in CLR/RAMP1 and CLR/RAMP2-mediated pro-angiogenic effect of intermedin on human vascular endothelial cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

calcitonin gene-related peptide receptor activity

determination method or standard

3 references

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

coreceptor activity

determination method or standard

3 references

amylin receptor activity

determination method or standard

calcitonin gene-related peptide binding

determination method or standard

1 reference

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

plasma membrane

determination method or standard

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

receptor complex

determination method or standard

1 reference

3 January 2017

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

integral component of plasma membrane

determination method or standard

1 reference

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

intracellular anatomical structure

determination method or standard

1 reference

3 January 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

determination method or standard

1 reference

3 January 2017

Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

extracellular space

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

determination method or standard

amylin receptor complex 1

determination method or standard

1 reference

9 May 2019

Amyloid β (Aβ) Peptide Directly Activates Amylin-3 Receptor Subtype by Triggering Multiple Intracellular Signaling Pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

CGRP receptor complex

determination method or standard

biological process

G protein-coupled receptor signaling pathway

determination method or standard

1 reference

3 January 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

positive regulation of protein glycosylation

determination method or standard

1 reference

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

determination method or standard

1 reference

3 January 2017

Involvement of vascular endothelial growth factor signaling in CLR/RAMP1 and CLR/RAMP2-mediated pro-angiogenic effect of intermedin on human vascular endothelial cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

determination method or standard

1 reference

3 January 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

protein transport

determination method or standard

1 reference

3 January 2017

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

protein localization to plasma membrane

determination method or standard

1 reference

3 January 2017

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

intracellular protein transport

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

calcium ion transport

determination method or standard

1 reference

3 January 2017

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60894

determination method or standard

determination method or standard

calcium ion transport

determination method or standard

G protein-coupled receptor signaling pathway

determination method or standard

3 references

adenylate cyclase-activating G protein-coupled receptor signaling pathway

determination method or standard

4 references

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Amyloid β (Aβ) Peptide Directly Activates Amylin-3 Receptor Subtype by Triggering Multiple Intracellular Signaling Pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

regulation of G protein-coupled receptor signaling pathway

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

protein transport

determination method or standard

receptor internalization

determination method or standard

4 references

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

cellular response to hormone stimulus

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60894

determination method or standard

protein localization to plasma membrane

determination method or standard

amylin receptor signaling pathway

determination method or standard

calcitonin gene-related peptide receptor signaling pathway

determination method or standard

physically interacts with

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2103758

Identifiers

MeSH descriptor ID

subject named as

Receptor Activity-Modifying Protein 1

0 references

D12.776.476.024.414.100

broader concept

receptor activity-modifying protein

0 references

D12.776.543.725.100

broader concept

receptor activity-modifying protein

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000254661

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000254661

ENSP00000384688

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384688

ENSP00000386046

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000386046

ENSP00000386720

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000386720

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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