Jump to content

Lysine acetyltransferase 2B (Q7118491)

From Wikidata
mammalian protein found in Homo sapiens
  • KAT2B
  • p300/CBP-associated factor
  • p300-CBP-Associated Factor
  • histone acetyltransferase PCAF
  • CREBBP-associated factor
  • histone acetyltransferase KAT2B
  • spermidine acetyltransferase KAT2B
  • histone acetylase PCAF
  • P/CAF
  • K(lysine) acetyltransferase 2B
edit
Language Label Description Also known as
default for all languages
No label defined
    English
    Lysine acetyltransferase 2B
    mammalian protein found in Homo sapiens
    • KAT2B
    • p300/CBP-associated factor
    • p300-CBP-Associated Factor
    • histone acetyltransferase PCAF
    • CREBBP-associated factor
    • histone acetyltransferase KAT2B
    • spermidine acetyltransferase KAT2B
    • histone acetylase PCAF
    • P/CAF
    • K(lysine) acetyltransferase 2B

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    26 references
    retrieved
    8 April 2019
    stated in
    A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1.
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development.
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Histone acetyltransferase-dependent chromatin remodeling and the vascular clock
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of E2A activities by histone acetyltransferases in B lymphocyte development
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    p66alpha and p66beta of the Mi-2/NuRD complex mediate MBD2 and histone interaction
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    E1A directly binds and regulates the P/CAF acetyltransferase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Twist and p53 reciprocally regulate target genes via direct interaction
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    H3K9 histone methyltransferase G9a-mediated transcriptional activation of p21
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Interaction of the HPV E7 proteins with the pCAF acetyltransferase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Histone-like TAFs within the PCAF histone acetylase complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cell density‐dependent acetylation of ΔNp63α is associated with p53‐dependent cell cycle arrest
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SIRT2 induces the checkpoint kinase BubR1 to increase lifespan
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A role of DNA-PK for the metabolic gene regulation in response to insulin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IPI
    histone acetyltransferase activity
    determination method or standard
    IEA
    IDA
    IMP
    EXP
    6 references
    retrieved
    8 April 2019
    stated in
    PCAF modulates PTEN activity
    GOA
    curator
    Community Assessment of Community Annotation with Ontologies
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Histone acetyltransferase-dependent chromatin remodeling and the vascular clock
    GOA
    curator
    UniProt
    UniProt protein ID
    Q92831
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831
    determination method or standard
    EXP
    cell component
    biological process
    Gene Atlas image
    PBB GE PCAF 203845 at fs.png
    732 × 530; 11 KB
    0 references

    Identifiers

    MeSH descriptor ID
    D000099224
    subject named as
    p300-CBP-Associated Factor
    0 references
    PDB structure ID
     
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    edit
                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q7118491&oldid=2450817459"