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SMAD family member 2 (Q6917574)

From Wikidata
mammalian protein found in Homo sapiens
  • MAD homolog 2
  • SMAD2
  • JV18-1
  • SMAD, mothers against DPP homolog 2
  • hMAD-2
  • Mad-related protein 2
  • mother against DPP homolog 2
  • SMAD 2
  • hSMAD2
  • mothers against decapentaplegic homolog 2
  • Sma- and Mad-related protein 2
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    English
    SMAD family member 2
    mammalian protein found in Homo sapiens
    • MAD homolog 2
    • SMAD2
    • JV18-1
    • SMAD, mothers against DPP homolog 2
    • hMAD-2
    • Mad-related protein 2
    • mother against DPP homolog 2
    • SMAD 2
    • hSMAD2
    • mothers against decapentaplegic homolog 2
    • Sma- and Mad-related protein 2

    Statements

    instance of
    R-SMAD
    0 references
    subclass of
    SMAD protein
    0 references
    molecular function
    protein binding
    determination method or standard
    IPI
    49 references
    retrieved
    8 April 2019
    stated in
    Cloning and functional characterization of a new Ski homolog, Fussel-18, specifically expressed in neuronal tissues
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    C18 ORF1, a novel negative regulator of transforming growth factor-β signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Potentiation of Smad-mediated transcriptional activation by the RNA-binding protein RBPMS
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ZNF580, a novel C2H2 zinc-finger transcription factor, interacts with the TGF-β signal molecule Smad2
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Roles of pathway-specific and inhibitory Smads in activin receptor signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    USP15 is a deubiquitylating enzyme for receptor-activated SMADs
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Functional proteomics mapping of a human signaling pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A Pin1/mutant p53 axis promotes aggressiveness in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    TIF1gamma controls erythroid cell fate by regulating transcription elongation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-β cytostatic program and blocks the antiproliferative effect of TGF-β
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Intercellular variation in signaling through the TGF-β pathway and its relation to cell density and cell cycle phase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Toward an understanding of the protein interaction network of the human liver
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural basis of heteromeric smad protein assembly in TGF-beta signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IPI
    cell component
    nucleus
    determination method or standard
    IDA
    IEA
    9 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    ZNF580, a novel C2H2 zinc-finger transcription factor, interacts with the TGF-β signal molecule Smad2
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Cellular response to hypoxia involves signaling via Smad proteins
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    biological process
    transforming growth factor beta receptor signaling pathway
    determination method or standard
    IDA
    TAS
    IMP
    IEA
    8 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    SMAD proteins control DROSHA-mediated microRNA maturation
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    positive regulation of transcription, DNA-templated
    determination method or standard
    IDA
    ISS
    IEA
    IMP
    7 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q15796
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15796
    determination method or standard
    IDA
    Gene Atlas image
    PBB GE SMAD2 203075 at fs.png
    732 × 530; 11 KB
    0 references

    Identifiers

    MeSH descriptor ID
    D051899
    subject named as
    Smad2 Protein
    0 references
     
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                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q6917574&oldid=2426562160"