Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain) (Q68127933)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1587832%20AND%20SRC:MED&resulttype=core&format=json

22 September 2019

title

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain) (English)

1 reference

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22 September 2019

author name string

DeMartino GN

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1587832%20AND%20SRC:MED&resulttype=core&format=json

22 September 2019

C.P. Ma

1

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C.A. Slaughter

2

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G.N. DeMartino

3

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C. P. Ma

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1587832

11 October 2022

C. A. Slaughter

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1587832

11 October 2022

G. N. DeMartino

3

1 reference

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11 October 2022

publication date

1 May 1992

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22 September 2019

May 1992

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25 May 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1587832

http://intl.jbc.org/cgi/content/abstract/267/15/10515

11 October 2022

language of work or name

English

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work available at URL

online access status

open access

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Journal of Biological Chemistry

11 October 2022

published in

1 reference

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22 September 2019

volume

267

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22 September 2019

issue

15

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22 September 2019

page(s)

10515-10523

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The multicatalytic proteinase of mammalian cells

22 September 2019

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The primary structures of four subunits of the human, high-molecular-weight proteinase, macropain (proteasome), are distinct but homologous

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ATP-stimulated proteolysis in soluble extracts of BHK 21/C13 cells. Evidence for multiple pathways and a role for an enzyme related to the high-molecular-weight protease, macropain

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The latent form of macropain (high molecular weight multicatalytic protease) restores ATP-dependent proteolysis to soluble extracts of BHK fibroblasts pretreated with anti-macropain antibodies

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ATP-stimulated degradation of endogenous proteins in cell free extracts of BHK 21/C13 fibroblasts A key role for the proteinase, macropain, in the ubiquitin-dependent degradation of short-lived proteins

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Purification and characterization of a protein inhibitor of the 20S proteasome (macropain)

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Pituitary multicatalytic proteinase complex. Specificity of components and aspects of proteolytic activity

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Identifiers

DOI

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1 reference